Robert Petryszak

TL;DR: The flagship paper of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium describes the generation of the integrative analyses of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types, the structures for international data sharing and standardized analyses, and the main scientific findings from across the consortium studies.

TL;DR: The main development over the last two years has been the release of a new data submission tool Annotare, which has reduced the average submission time almost 3-fold and will become the only submission route into ArrayExpress, alongside MAGE-TAB format-based pipelines in the near future.

TL;DR: The latest InterPro release (13.0) contains more than 13 000 entries, covering over 78% of all proteins in UniProtKB, and there have been several new developments in InterPro, including an additional reading field, new database links, extensions to the web interface and additional match XML files.

TL;DR: The first proteomics study in human tissues is now displayed alongside transcriptomics data in the same tissues, and novel analyses and visualisations include: ‘enrichment’ in each differential comparison of GO terms, Reactome, Plant Reactome pathways and InterPro domains.

TL;DR: With an increasing number of studies that combine different assay modalities (multi-omics experiments), a new more general archival resource the BioStudies Database has been developed, which will eventually supersede ArrayExpress.