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Robert Tibshirani
Researcher at Stanford University
Publications - 620
Citations - 359457
Robert Tibshirani is an academic researcher from Stanford University. The author has contributed to research in topics: Lasso (statistics) & Gene expression profiling. The author has an hindex of 147, co-authored 593 publications receiving 326580 citations. Previous affiliations of Robert Tibshirani include University of Toronto & University of California.
Papers
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Journal ArticleDOI
Survival analysis with high-dimensional covariates.
Daniela Witten,Robert Tibshirani +1 more
TL;DR: A number of methods from the literature are reviewed that address the problems of identifying features that are associated with survival and developing a multivariate model for the relationship between the features and survival that can be used to predict survival in a new observation.
Journal ArticleDOI
Hierarchical Clustering With Prototypes via Minimax Linkage.
Jacob Bien,Robert Tibshirani +1 more
TL;DR: It is proved that minimax linkage has a number of desirable theoretical properties; for example, minimax-linkage dendrograms cannot have inversions (unlike centroid linkage) and is robust against certain perturbations of a dataset.
Patent
Significance analysis of microarrays
TL;DR: Significance analysis of microarrays (SAM) as mentioned in this paper assigns a score to each gene based on the change in gene expression relative to the standard deviation of repeated measurements, and uses permutations of the repeated measurements to estimate the percentage of such genes identified by chance, the false discovery rate.
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An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging
Nazish Sayed,Yingxiang Huang,Khiem Van Nguyen,Zuzana Krejciova-Rajaniemi,Anissa P. Grawe,Tianxiang Gao,Robert Tibshirani,Trevor Hastie,Ayelet Alpert,Lu Cui,Tatiana Kuznetsova,Yael Rosenberg-Hasson,Rita Ostan,Daniela Monti,Benoit Lehallier,Shai S. Shen-Orr,Holden T. Maecker,Cornelia L. Dekker,Tony Wyss-Coray,Claudio Franceschi,Vladimir Jojic,Francois Haddad,Jose G. Montoya,Joseph C. Wu,Mark M. Davis,David Furman +25 more
TL;DR: A key role is identified in age-related chronic inflammation of CXCL9 in cardiac aging, adverse cardiac remodeling and poor vascular function and a metric for multimorbidity is derived that can be utilized for the early detection of age- related clinical phenotypes.
Journal ArticleDOI
Diagnosis of Prostate Cancer by Desorption Electrospray Ionization Mass Spectrometric Imaging of Small Metabolites and Lipids
Shibdas Banerjee,Richard N. Zare,Robert Tibshirani,Christian A. Kunder,Rosalie Nolley,Richard E. Fan,James D. Brooks,Geoffrey A. Sonn +7 more
TL;DR: Measurement of the glucose/citrate ion signal ratio accurately predicted cancer when this ratio exceeds 1.0 and normal prostate when the ratio is less than 0.5, indicated that the ratio of glucose to citrate ion signals could be used to accurately identify prostate cancer.