R
Robert W. Taylor
Researcher at Vanderbilt University
Publications - 13
Citations - 30528
Robert W. Taylor is an academic researcher from Vanderbilt University. The author has contributed to research in topics: VUAA1 & Receptor. The author has an hindex of 11, co-authored 12 publications receiving 20479 citations. Previous affiliations of Robert W. Taylor include Western Kentucky University.
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Journal ArticleDOI
Research electronic data capture (REDCap)-A metadata-driven methodology and workflow process for providing translational research informatics support
Paul A. Harris,Robert W. Taylor,Robert J. Thielke,Jonathon Payne,Nathaniel Gonzalez,José G. Conde +5 more
TL;DR: Research electronic data capture (REDCap) is a novel workflow methodology and software solution designed for rapid development and deployment of electronic data Capture tools to support clinical and translational research.
Journal ArticleDOI
Procurement of shared data instruments for Research Electronic Data Capture (REDCap)
Jihad S. Obeid,Catherine A. Mcgraw,Brenda L. Minor,José G. Conde,Robert Pawluk,Michael Lin,Janey Wang,Sean R. Banks,Sheree A. Hemphill,Robert W. Taylor,Paul A. Harris +10 more
TL;DR: The library platform is described, detail is provided about experience gained during the first 25months of sharing public domain instruments and evidence of impact is provided for the SDIL across the REDCap consortium research community.
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Allosteric Antagonism of Insect Odorant Receptor Ion Channels
Patrick L. Jones,Gregory M. Pask,Ian M. Romaine,Robert W. Taylor,Paul R Reid,Alex G. Waterson,Alex G. Waterson,Gary A. Sulikowski,Laurence J. Zwiebel +8 more
TL;DR: The first Orco antagonist is described and characterized, capable of non-competitively inhibiting odorant-evoked activation of OR complexes, thereby providing additional insight into the structure/function of this unique family of ligand-gated ion channels.
Journal ArticleDOI
Structure–Activity Relationship of a Broad-Spectrum Insect Odorant Receptor Agonist
Robert W. Taylor,Ian M. Romaine,Ian M. Romaine,Chao Liu,Chao Liu,Poornima Murthi,Poornima Murthi,Patrick L. Jones,Patrick L. Jones,Alex G. Waterson,Alex G. Waterson,Gary A. Sulikowski,Gary A. Sulikowski,Laurence J. Zwiebel,Laurence J. Zwiebel +14 more
TL;DR: The chemical space around VUAA1, the first in class agonist of the obligate OR co-receptor ion channel, is explored, and novel compound analogues with increased potency across insect taxa are described.
Journal ArticleDOI
A conserved aspartic acid is important for agonist (VUAA1) and odorant/tuning receptor-dependent activation of the insect odorant co-receptor (Orco).
Brijesh Kumar,Robert W. Taylor,Gregory M. Pask,Laurence J. Zwiebel,Richard D. Newcomb,Richard D. Newcomb,David L. Christie +6 more
TL;DR: The gain-of-activation characteristic of the D466E mutant identifies an amino acid that is likely to be important for activation of both heteromeric and homomeric insect odorant receptor channels.