R
Roberto Romero
Researcher at National Institutes of Health
Publications - 1622
Citations - 121818
Roberto Romero is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Amniotic fluid & Pregnancy. The author has an hindex of 151, co-authored 1516 publications receiving 108321 citations. Previous affiliations of Roberto Romero include University of Michigan & Weizmann Institute of Science.
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Journal ArticleDOI
Intrauterine Infection, Preterm Labor, and Cytokines
TL;DR: Preterm parturition is now considered a syndrome caused by multiple pathologic processes able to activate the common terminal pathway ofParturition and mortality worldwide.
Journal ArticleDOI
The frequency and clinical significance of intra-amniotic infection and/or inflammation in women with placenta previa and vaginal bleeding: an unexpected observation
Ichchha Madan,Roberto Romero,Juan Pedro Kusanovic,Pooja Mittal,Tinnakorn Chaiworapongsa,Zhong Dong,Shali Mazaki-Tovi,Edi Vaisbuch,Zeynep Alpay Savasan,Lami Yeo,Chong Jai Kim,Sonia S. Hassan +11 more
TL;DR: Patients with placenta previa presenting with vaginal bleeding have intra-amniotic infection in 5.7% of the cases, and IAI in 17.9%, which is a risk factor for preterm delivery within 48 h.
Journal ArticleDOI
GROα in the fetomaternal and amniotic fluid compartments during pregnancy and parturition
Jose Cohen,Fabio Ghezzi,Roberto Romero,Roberto Romero,Alessandro Ghidini,Moshe Mazor,Jorge E. Tolosa,Luis F. Gonçalves,Ricardo Gomez +8 more
TL;DR: The use of monoclonal antibodies for CD45RA and CD45RO antigens is important in defining maturational and functional stages on lymphocytes.
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Human trophoblast survival at low oxygen concentrations requires metalloproteinase-mediated shedding of heparin-binding EGF-like growth factor
D. Randall Armant,Brian A. Kilburn,Anelia P. Petkova,Samuel Edwin,Zophia M. Duniec-Dmuchowski,Holly Edwards,Roberto Romero,Richard Leach +7 more
TL;DR: Evidence is provided that a post-transcriptional mechanism induced in trophoblasts by low O2 rapidly amplifies HBEGF signaling to inhibit apoptosis, which is likely to be a contributing factor leading to the demise of trophoblast survival.
Journal ArticleDOI
Risk factors for the development of preterm premature rupture of the membranes after arrest of preterm labor
Debra A. Guinn,Robert L. Goldenberg,John C. Hauth,William W. Andrews,Elizabeth Thom,Roberto Romero +5 more
TL;DR: Black race, multiparity, a history of abortion or preterm birth, advanced dilatation, and a positive amniotic fluid marker(s) are associated with preterm premature rupture of the membranes in women with pre term labor.