R
Roberto Romero
Researcher at National Institutes of Health
Publications - 1622
Citations - 121818
Roberto Romero is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Amniotic fluid & Pregnancy. The author has an hindex of 151, co-authored 1516 publications receiving 108321 citations. Previous affiliations of Roberto Romero include University of Michigan & Weizmann Institute of Science.
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Journal ArticleDOI
Interleukin-1 stimulates prostaglandin biosynthesis by human amnion.
Roberto Romero,Scott K. Durum,Charles A. Dinarello,E. Oyarzun,John C. Hobbins,Murray D. Mitchell +5 more
TL;DR: Indomethacin blocked the effect of IL-1 in prostaglandin biosynthesis by human amnion, and Interleukin-1, a fever mediator, could serve as a signal for the initiation of labor in cases of intrauterine or systemic infection.
Journal ArticleDOI
Vaginal Progesterone for Preventing Preterm Birth and Adverse Perinatal Outcomes in Singleton Gestations with a Short Cervix: A Meta-Analysis of Individual Patient Data
Roberto Romero,Agustin Conde-Agudelo,Eduardo Ribeiro da Fonseca,John M. O'Brien,Elcin Cetingoz,George W. Creasy,Sonia S. Hassan,Kypros H. Nicolaides +7 more
TL;DR: Vaginal progesterone decreases the risk of preterm birth and improves perinatal outcomes in singleton gestations with a midtrimester sonographic short cervix, without any demonstrable deleterious effects on childhood neurodevelopment.
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Macrophages and Apoptotic Cell Clearance During Pregnancy
TL;DR: This work has shown that during implantation, apoptosis is critical for the appropriate tissue remodeling of the maternal decidua and invasion of the developing embryo, yet the regulation of apoptotic cells is also imperative for a successful pregnancy.
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Evolution of the mammalian placenta revealed by phylogenetic analysis
Derek E. Wildman,Caoyi Chen,Offer Erez,Offer Erez,Lawrence I. Grossman,Morris Goodman,Roberto Romero,Roberto Romero +7 more
TL;DR: Using phylogenetic and statistical analyses of molecular and morphological data, it is demonstrated that the ancestral eutherian mammalian placenta had the distinctive features of (i) hemochorial placental interface, (ii) a discoid shape, and (iii) a labyrinthine maternofetal interdigitation.
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Clinical significance of intra-amniotic inflammation in patients with preterm premature rupture of membranes
Soon-Sup Shim,Roberto Romero,Joon-Seok Hong,Chan-Wook Park,Jong Kwan Jun,Beyong Il Kim,Bo Hyun Yoon +6 more
TL;DR: In this paper, the frequency and clinical significance of intra-amniotic inflammation in patients with preterm premature rupture of the membranes was determined, and the authors concluded that intraamniotic inflammatory markers are a risk factor for impending preterm delivery and adverse outcome.