R
Roberto Romero
Researcher at National Institutes of Health
Publications - 1622
Citations - 121818
Roberto Romero is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Amniotic fluid & Pregnancy. The author has an hindex of 151, co-authored 1516 publications receiving 108321 citations. Previous affiliations of Roberto Romero include University of Michigan & Weizmann Institute of Science.
Papers
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Journal ArticleDOI
Systemic and local cytokine profiles in endotoxin-induced preterm parturition in mice
Paul L. Fidel,Roberto Romero,Norbert A. Wolf,Jessica Cutright,Marcelo Ramirez,Heriberto Araneda,David B. Cotton +6 more
TL;DR: Preterm delivery after lipopolysaccharide administration is preceded by the appearance of dramatic increases in maternal serum concentrations of tumor necrosis factor-α, interleukin-6, and interleukain-1α and in amniotic fluid concentrations of interleucin- 6 and interLEukin -1α.
Journal Article
Human decidua: a source of interleukin-1.
TL;DR: It is demonstrated that human decidua can produce interleukin-1 in response to bacterial endotoxin, as demonstrated by the blockade of this bioactivity with antibodies againstinterleuk in-1: interleukesin-i alpha and interleuko-1 beta.
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A System of Cytokines Encapsulated in ExtraCellular Vesicles
Wendy Fitzgerald,Michael L. Freeman,Michael M. Lederman,Elena Vasilieva,Roberto Romero,Leonid Margolis +5 more
TL;DR: It is demonstrated that these two systems of cell–cell communication are not strictly separated, as many cytokines in vitro, ex vivo, and in vivo are released in EV-encapsulated forms and are capable of eliciting biological effects upon contact with sensitive cells.
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Toll-like receptor-2 and -4 in the chorioamniotic membranes in spontaneous labor at term and in preterm parturition that are associated with chorioamnionitis
Yeon Mee Kim,Roberto Romero,Tinnakorn Chaiworapongsa,Gi Jin Kim,Mi Ran Kim,Helena Kuivaniemi,Gerard Tromp,Jimmy Espinoza,Emmanuel Bujold,Vikki M. Abrahams,Gil Mor +10 more
TL;DR: In this paper, the authors examined the expression of the Toll-like receptor-2 and -4 in fetal membranes in response to labor at term and histologic chorioamnionitis.
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Amniotic fluid interleukin-6 : correlation with upper genital tract microbial colonization and gestational age in women delivered after spontaneous labor versus indicated delivery
William W. Andrews,John C. Hauth,Robert L. Goldenberg,Ricardo Gomez,Roberto Romero,Gail H. Cassell +5 more
TL;DR: Amniotic fluid interleukin-6 levels are higher and inversely proportional to gestational age in women with intact membranes and spontaneous labor versus indicated deliveries, higher in women in whom both cultures were negative, and reflective of chorioamnion microbial colonization.