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Roberto Romero

Researcher at National Institutes of Health

Publications -  1622
Citations -  121818

Roberto Romero is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Amniotic fluid & Pregnancy. The author has an hindex of 151, co-authored 1516 publications receiving 108321 citations. Previous affiliations of Roberto Romero include University of Michigan & Weizmann Institute of Science.

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Systemic and local cytokine profiles in endotoxin-induced preterm parturition in mice

TL;DR: Preterm delivery after lipopolysaccharide administration is preceded by the appearance of dramatic increases in maternal serum concentrations of tumor necrosis factor-α, interleukin-6, and interleukain-1α and in amniotic fluid concentrations of interleucin- 6 and interLEukin -1α.
Journal Article

Human decidua: a source of interleukin-1.

TL;DR: It is demonstrated that human decidua can produce interleukin-1 in response to bacterial endotoxin, as demonstrated by the blockade of this bioactivity with antibodies againstinterleuk in-1: interleukesin-i alpha and interleuko-1 beta.
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A System of Cytokines Encapsulated in ExtraCellular Vesicles

TL;DR: It is demonstrated that these two systems of cell–cell communication are not strictly separated, as many cytokines in vitro, ex vivo, and in vivo are released in EV-encapsulated forms and are capable of eliciting biological effects upon contact with sensitive cells.
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Amniotic fluid interleukin-6 : correlation with upper genital tract microbial colonization and gestational age in women delivered after spontaneous labor versus indicated delivery

TL;DR: Amniotic fluid interleukin-6 levels are higher and inversely proportional to gestational age in women with intact membranes and spontaneous labor versus indicated deliveries, higher in women in whom both cultures were negative, and reflective of chorioamnion microbial colonization.