R
Roberto Romero
Researcher at National Institutes of Health
Publications - 1622
Citations - 121818
Roberto Romero is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Amniotic fluid & Pregnancy. The author has an hindex of 151, co-authored 1516 publications receiving 108321 citations. Previous affiliations of Roberto Romero include University of Michigan & Weizmann Institute of Science.
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A Role for TLRs in the Regulation of Immune Cell Migration by First Trimester Trophoblast Cells
TL;DR: It is demonstrated that human first trimester trophoblast cells constitutively secrete the chemokines growth-related oncogene, growth- related oncogenic α, IL-8, and MCP-1 and are able to recruit monocytes and NK cells, and to a lesser degree, neutrophils, and this in turn results in elevated monocyte and neutrophil chemotaxis.
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Viral Infection of the Placenta Leads to Fetal Inflammation and Sensitization to Bacterial Products Predisposing to Preterm Labor
Ingrid Cardenas,Robert E. Means,Paulomi Aldo,Kaori Koga,Sabine Lang,Carmen J. Booth,Alejandro Manzur,Enrique Oyarzun,Roberto Romero,Gil Mor +9 more
TL;DR: An animal model is developed to evaluate the consequences of a viral infection characterized by lack of fetal transmission and shows that viral infection of the placenta can elicit a fetal inflammatory response that can cause organ damage and potentially downstream developmental deficiencies.
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Amniotic fluid white blood cell count: a rapid and simple test to diagnose microbial invasion of the amniotic cavity and predict preterm delivery.
Roberto Romero,Rubén A. Quintero,Jose Nores,Cecilia Avila,Moshe Mazor,Shuichi Hanaoka,Zion Hagay,Lydia Merchant,John C. Hobbins +8 more
TL;DR: It is concluded that the amniotic fluid white blood cell count is a sensitive, simple, and inexpensive test for the detection of microbial invasion of theAmniotic cavity.
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Extracellular matrix composition and hypoxia regulate the expression of HLA-G and integrins in a human trophoblast cell line.
Brian A. Kilburn,Jun Wang,Zophia M. Duniec-Dmuchkowski,Richard Leach,Roberto Romero,D. Randall Armant +5 more
TL;DR: HTR-8/SVneo cells retain several important characteristics associated with primary cultures of first-trimester human cytotrophoblast cells, including their altered behavior in response to a changing maternal environment.
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Transvaginal sonographic cervical length for the prediction of spontaneous preterm birth in twin pregnancies: a systematic review and metaanalysis
Agustin Conde-Agudelo,Roberto Romero,Roberto Romero,Sonia S. Hassan,Sonia S. Hassan,Lami Yeo,Lami Yeo +6 more
TL;DR: Transvaginal sonographic CL at 20-24 weeks' gestation is a good predictor of spontaneous preterm birth in asymptomatic women with twin pregnancies.