R
Roberto Romero
Researcher at National Institutes of Health
Publications - 1622
Citations - 121818
Roberto Romero is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Amniotic fluid & Pregnancy. The author has an hindex of 151, co-authored 1516 publications receiving 108321 citations. Previous affiliations of Roberto Romero include University of Michigan & Weizmann Institute of Science.
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Journal ArticleDOI
The Isolation and Characterization of a Novel Telomerase Immortalized First Trimester Trophoblast Cell Line, Swan 71
Shawn L. Straszewski-Chavez,Vikki M. Abrahams,Ayesha B. Alvero,Paulomi Aldo,Yuehong Ma,Seth Guller,Roberto Romero,Gil Mor +7 more
TL;DR: This work isolated primary trophoblast cells from a 7-week normal placenta and infected the cells with human telomerase reverse transcriptase (hTERT), the catalytic subunit of telomersase, leading to a new cell line that is resistant to Fas, but not TNF-alpha-induced apoptosis.
Journal ArticleDOI
The clinical significance of detecting Ureaplasma urealyticum by the polymerase chain reaction in the amniotic fluid of patients with preterm labor.
Bo Hyun Yoon,Roberto Romero,June-Hee Lim,Soon-Sup Shim,Joon-Seok Hong,Jae-Yoon Shim,Jong Kwan Jun +6 more
TL;DR: In this article, a study was conducted to determine the clinical significance of a detection of Ureaplasma urealyticum by using the polymerase chain reaction (PCR) in the amniotic fluid of patients with preterm labor and intact membranes.
Journal ArticleDOI
Damage-associated molecular patterns (DAMPs) in preterm labor with intact membranes and preterm PROM: a study of the alarmin HMGB1.
Roberto Romero,Tinnakorn Chaiworapongsa,Zeynep Alpay Savasan,Yi Xu,Youssef Hussein,Zhong Dong,Juan Pedro Kusanovic,Chong Jai Kim,Sonia S. Hassan +8 more
TL;DR: This study determined whether intra-amniotic infection/inflammation (IAI) is associated with changes in amniotic fluid concentrations of HMGB1; and localize immunoreactivity ofHMGB1 in the fetal membranes and umbilical cord of patients with chorioamnionitis.
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Clinical chorioamnionitis at term I: microbiology of the amniotic cavity using cultivation and molecular techniques.
Roberto Romero,Jezid Miranda,Juan Pedro Kusanovic,Tinnakorn Chaiworapongsa,Piya Chaemsaithong,Piya Chaemsaithong,A Martínez,Francesca Gotsch,Zhong Dong,Ahmed I. Ahmed,Majid Shaman,Kia Lannaman,Bo Hyun Yoon,Sonia S. Hassan,Sonia S. Hassan,Chong J. Kim,Steven J. Korzeniewski,Steven J. Korzeniewski,Lami Yeo,Lami Yeo,Yeon Mee Kim +20 more
TL;DR: The amniotic fluid (AF) microbiology of patients with the diagnosis of clinical chorioamnionitis at term was determined using both cultivation and molecular techniques and the relationship between intra-amniotic inflammation with and without microorganisms and placental lesions consistent with acute AF infection was examined.
Journal Article
Amniotic fluid interleukin-1 in spontaneous labor at term.
Roberto Romero,S.T. Parvizi,E. Oyarzun,Moshe Mazor,Ying King Wu,Cecilia Avila,Apostolos P. Athanassiadis,Mitchell +7 more
TL;DR: Data show that inhibitors of IL-1 bioactivity are present in amniotic fluid and suggest that in a subset of laboring women at term, an inflammatory reaction may play a role in triggering the onset of parturition.