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Roberto Romero

Researcher at National Institutes of Health

Publications -  1622
Citations -  121818

Roberto Romero is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Amniotic fluid & Pregnancy. The author has an hindex of 151, co-authored 1516 publications receiving 108321 citations. Previous affiliations of Roberto Romero include University of Michigan & Weizmann Institute of Science.

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Nifedipine in the management of preterm labor: a systematic review and metaanalysis

TL;DR: Nifedipine is superior to β₂-adrenergic-receptor agonists and magnesium sulfate for tocolysis in women with preterm labor and is associated with significantly fewer maternal adverse events.
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The preterm parturition syndrome and its implications for understanding the biology, risk assessment, diagnosis, treatment and prevention of preterm birth.

TL;DR: The syndromic nature of spontaneous labour was a concept first proposed in 1994 and this article outlines the potential flaws in this concept, which it is believed has halted progress in the prevention of pre term birth and in the treatment of preterm labour.
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Midtrimester amniotic fluid concentrations of interleukin-6 and interferon-gamma-inducible protein-10: evidence for heterogeneity of intra-amniotic inflammation and associations with spontaneous early ( 32 weeks) preterm delivery.

TL;DR: Although each type of inflammation is a risk factor for spontaneous preterm delivery, many patients had a term delivery without complication; and the amniotic fluid in the midtrimester did not contain microorganisms detectable with cultivation techniques.
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An M1-like Macrophage Polarization in Decidual Tissue during Spontaneous Preterm Labor That Is Attenuated by Rosiglitazone Treatment.

TL;DR: It is demonstrated that decidual M1-like macrophages are associated with spontaneous preterm labor and that PPARγ activation via RSG can attenuate the macrophage-mediated proinflammatory response, preventing preterm birth and improving neonatal outcomes.
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Maternal blood C-reactive protein, white blood cell count, and temperature in preterm labor: a comparison with amniotic fluid white blood cell count.

TL;DR: An elevated C-reactive protein, WBC, or AF WBC identified patients with intrauterine infection and adverse perinatal outcomes as well as patients with acute histologic chorioamnionitis.