R
Roberto Romero
Researcher at National Institutes of Health
Publications - 1622
Citations - 121818
Roberto Romero is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Amniotic fluid & Pregnancy. The author has an hindex of 151, co-authored 1516 publications receiving 108321 citations. Previous affiliations of Roberto Romero include University of Michigan & Weizmann Institute of Science.
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Journal ArticleDOI
Abnormal concentration of maternal serum activin-A in gestational diseases
Felice Petraglia,Davide De Vita,Andrea Gallinelli,L. Aguzzoli,Andrea R. Genazzani,Roberto Romero,Teresa K. Woodruff +6 more
TL;DR: It is shown that preterm labor is associated with increased concentrations of activin-A in the maternal circulation and cord serum, and Hypersecretion of activIn-A is also shown in same patients with gestation diabetes; this reverts to normal after insulin treatment.
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Progesterone receptor isoform (A/B) ratio of human fetal membranes increases during term parturition
Soo-young Oh,Chong Jai Kim,Insuk Park,Roberto Romero,Yoo-Kyung Sohn,Kyung Chul Moon,Bo Hyun Yoon +6 more
TL;DR: Human parturition at term is associated with changes in PR isoforms in the fetal membranes and, thus, a local 'functional progesterone withdrawal' may operate in human parturitions through this mechanism.
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Intraamniotic infection with genital mycoplasmas exhibits a more intense inflammatory response than intraamniotic infection with other microorganisms in patients with preterm premature rupture of membranes
Kyung Joon Oh,Kyung A. Lee,Yoo Kyung Sohn,Chan-Wook Park,Joon Seok Hong,Roberto Romero,Bo Hyun Yoon +6 more
TL;DR: Intraamniotic and maternal inflammatory responses are more intense in intraamniotic infection with genital mycoplasmas than in intraamiotics infection with other microorganisms in patients with preterm premature rupture of membranes.
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Recurrent Preterm Birth
Shali Mazaki-Tovi,Roberto Romero,Roberto Romero,Juan Pedro Kusanovic,Offer Erez,Beth L. Pineles,Francesca Gotsch,Pooja Mittal,Pooja Mittal,Nandor Gabor Than,Jimmy Espinoza,Sonia S. Hassan +11 more
TL;DR: The body of literature describing the risk of recurrence of spontaneous and indicated preterm birth is reviewed and the factors which modify the risk are discussed (a short sonographic cervical length and a positive cervicovaginal fetal fibronectin test).
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A role for the 72 kDa gelatinase (MMP-2) and its inhibitor (TIMP-2) in human parturition, premature rupture of membranes and intraamniotic infection.
Eli Maymon,Roberto Romero,Percy Pacora,Ricardo Gomez,Moshe Mazor,Sam Edwin,Tinnakorn Chaiworapongsa,Ju Cheol Kim,Bo Hyun Yoon,Ramkumar Menon,Stephen J. Fortunato,Stanley M. Berry +11 more
TL;DR: Human parturition (preterm and term), rupture of fetal membranes (term and preterm) and intraamniotic infection are associated with a significant decrease in amniotic fluid TIMP-2 concentrations.