R
Roberto Romero
Researcher at National Institutes of Health
Publications - 1622
Citations - 121818
Roberto Romero is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Amniotic fluid & Pregnancy. The author has an hindex of 151, co-authored 1516 publications receiving 108321 citations. Previous affiliations of Roberto Romero include University of Michigan & Weizmann Institute of Science.
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Pre-eclampsia and expression of heparin-binding EGF-like growth factor
Richard Leach,Roberto Romero,Yeon Mee Kim,Tinnakorn Chaiworapongsa,Brian A. Kilburn,Sanjoy K. Das,Sudhansu K. Dey,Anthony Johnson,Faisal Qureshi,Suzanne M. Jacques,D. Randall Armant +10 more
TL;DR: In pre-eclampsia, deficient HB-EGF signalling during placental development could impair trophoblast survival, differentiation, and invasion, leading to poor placental perfusion and hypertension.
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Phenotypic and metabolic characteristics of maternal monocytes and granulocytes in preterm labor with intact membranes
Maria Teresa Gervasi,Tinnakorn Chaiworapongsa,Nihal Naccasha,Sean C. Blackwell,Bo Hyun Yoon,Eli Maymon,Roberto Romero +6 more
TL;DR: Preterm labor with intact membranes is associated with phenotypic and metabolic changes of maternal granulocytes and monocytes, and it is proposed that parturition requires fetomaternal cooperation and that inflammation is an integral part of the parturitional process.
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Normal pregnancy is characterized by systemic activation of the complement system
Karina Richani,Eleazar Soto,Jimmy Espinoza,Jyh Kae Nien,Tinnakorn Chaiworapongsa,Samuel Edwin,Moshe Mazor,Roberto Romero +7 more
TL;DR: Normal human pregnancy is associated with evidence of complement activation, as determined by higher concentrations of the anaphylatoxins C3a, C4a and C5a in the maternal circulation, and it is proposed that physiologic activation of the complement system during pregnancy is a compensatory mechanism aimed at protecting the host against infection.
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Interleukin-1 and tumor necrosis factor stimulate arachidonic acid release and phospholipid metabolism in human myometrial cells
TL;DR: Both interleukin-1 and tumor necrosis factor enhance arachidonic acid release, probably by inducing the synthesis ofospholipase A2 and possibly other enzymes involved in the metabolism of phospholipids, in turn serving as the precursor for prostaglandins and various other bioactive eicosanoids.
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Does the endometrial cavity have a molecular microbial signature
Andrew D. Winters,Andrew D. Winters,Roberto Romero,Maria Teresa Gervasi,Nardhy Gomez-Lopez,Maria Rosa Tran,Valeria Garcia-Flores,Valeria Garcia-Flores,Percy Pacora,Percy Pacora,Eun Jung Jung,Eun Jung Jung,Sonia S. Hassan,Chaur-Dong Hsu,Kevin R. Theis,Kevin R. Theis +15 more
TL;DR: If there is a microbiota in the middle endometrium, it is not dominated by Lactobacillus as was previously concluded, yet further investigation using culture and microscopy is necessary.