Roberto Salvatori

TL;DR: Using an evidence-based approach, this guideline addresses important clinical issues regarding the evaluation and management of hypopituitarism in adults, including appropriate biochemical assessments, specific therapeutic decisions to decrease the risk of co-morbidities due to hormonal over-replacements or under-replacement, and managing hypopitsuits during pregnancy, pituitary surgery, and other types of surgeries.

TL;DR: Hypophysitis has emerged as a distinctive side effect of CTLA4-blocking antibodies, establishing a new form of autoimmune pituitary disease in patients affected by advanced cutaneous melanoma.

TL;DR: Prisposition for aggressive disease in young patients, often in a familial setting, suggests that earlier diagnosis of AIPmut pituitary adenomas may have clinical utility.

TL;DR: A novel mutation in the GHRHR gene is described as cause of dwarfism in the largest kindred with familial IGHD described to date, and thirty of the affected subjects tested were homozygous for this mutation.

TL;DR: The role of germline AIP, MEN1, PRKAR1A, CDKN1B and CDKN2C mutations in causing pituitary adenomas in a large cohort of children, adolescents, and patients with genetic syndromes is investigated.