Robin M. Murray

TL;DR: Functional magnetic resonance imaging provides evidence that interactions between the dopamine and the glutamate system, thought to be altered in psychosis, have an impact in executive processing which can be modulated by common genetic variation.

TL;DR: The case series fails to support the hypothesis that VGKC antibodies are linked to treatment resistance in psychosis, but the preliminary meta‐analysis suggests that GAD autoantibodies are more common in people with psychosis than in controls, although few studies accounted for the possibility of co‐existing type 1 diabetes mellitus and the clinical significance of reported GAD titers remains unclear.

TL;DR: It is concluded that there is unlikely to be a major gene in the 8p21-p22 region which confers susceptibility to schizophrenia in the set of families, however one cannot exclude the possibility of a major genes present in other families, or of a susceptibility gene with a moderate but widespread effect which one cannot detect.

TL;DR: Previous findings of association between PRODH and schizophrenia are taken further by associating variation within the gene with performance on a neurocognitive trait characteristic of the illness, but fails to confirm previous reports of an association between COMT and cognitive function.