R
Rogelio Hernández-Pando
Researcher at National Institute of Nutrition, Hyderabad
Publications - 364
Citations - 13726
Rogelio Hernández-Pando is an academic researcher from National Institute of Nutrition, Hyderabad. The author has contributed to research in topics: Tuberculosis & Mycobacterium tuberculosis. The author has an hindex of 60, co-authored 334 publications receiving 12173 citations. Previous affiliations of Rogelio Hernández-Pando include University of Medicine and Dentistry of New Jersey & Erasmus University Rotterdam.
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Journal ArticleDOI
A marked difference in pathogenesis and immune response induced by different Mycobacterium tuberculosis genotypes.
Beatriz López,Diana Aguilar,Héctor Fabio Bermúdez Orozco,M. Burger,Clara Espitia,Viviana Ritacco,Lucía Barrera,Kristin Kremer,Rogelio Hernández-Pando,Kris Huygen,D. van Soolingen +10 more
TL;DR: Genetically different M. tuberculosis strains evoked markedly different immunopathological events in mice, and future immunological research, particularly on candidate vaccines, should include a broad spectrum of M. TB genotypes rather than a few laboratory strains.
Journal ArticleDOI
Persistence of DNA from Mycobacterium tuberculosis in superficially normal lung tissue during latent infection.
Rogelio Hernández-Pando,Mangalakumari Jeyanathan,Getahun Mengistu,Diana Aguilar,Héctor Fabio Bermúdez Orozco,Morten Harboe,Graham A. W. Rook,Gunnar Bjune +7 more
TL;DR: Findings contradict the dominant view that latent organisms exist in old classic tuberculous lesions, and have important implications for strategies aimed at the elimination of latent and persistent bacilli.
Journal ArticleDOI
Is Adipose Tissue a Place for Mycobacterium tuberculosis Persistence
Olivier Neyrolles,Olivier Neyrolles,Rogelio Hernández-Pando,Paul Fornès,Ludovic Tailleux,Jorge Alberto Barrios Payan,Elisabeth Pivert,Yann Bordat,Diane Aguilar,Marie-Christine Prévost,Caroline Petit,Brigitte Gicquel +11 more
TL;DR: In vitro, using a combination of adipose cell models, it is shown that after binding to scavenger receptors, M. tuberculosis can enter within adipocytes, where it accumulates intracytoplasmic lipid inclusions and survives in a non-replicating state that is insensitive to the major anti-mycobacterial drug isoniazid.
Journal ArticleDOI
Hormones, peripherally activated prohormones and regulation of the Th1/Th2 balance
TL;DR: An important influence on this shift that has been largely ignored in in vitro work is the endocrine system.
Journal Article
Correlation between the kinetics of Th1, Th2 cells and pathology in a murine model of experimental pulmonary tuberculosis.
Rogelio Hernández-Pando,H Orozcoe,A. Sampieri,Lenin Pavón,C Velasquillo,Jorge Larriva-Sahd,J M Alcocer,M V Madrid +7 more
TL;DR: The results suggest that T-lymphocyte subset kinetics and the pattern of cytokines produced in the lung during tuberculosis infection changed over time and correlate with the type and magnitude of tissue injury.