R
Roger J. Packer
Researcher at Children's National Medical Center
Publications - 458
Citations - 34492
Roger J. Packer is an academic researcher from Children's National Medical Center. The author has contributed to research in topics: Medulloblastoma & Radiation therapy. The author has an hindex of 96, co-authored 445 publications receiving 30590 citations. Previous affiliations of Roger J. Packer include University of Pennsylvania & Children's Hospital of Philadelphia.
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Journal ArticleDOI
Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma.
Roger J. Packer,Amar Gajjar,Gilbert Vezina,Lucy B. Rorke-Adams,Peter C. Burger,Patricia L. Robertson,Lisa Bayer,Deborah Lafond,Bernadine Donahue,Mary Anne H. Marymont,Karin M. Muraszko,James Langston,Richard Sposto +12 more
TL;DR: An encouraging EFS rate for children with nondisseminated MB treated with reduced-dose craniospinal radiation and chemotherapy is disclosed and additional, careful, step-wise reductions in CSRT in adequately staged patients may be possible.
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Central nervous system atypical teratoid/rhabdoid tumors of infancy and childhood: definition of an entity
TL;DR: Clinical and pathological features of 52 infants and children with atypical teratoid/rhabdoid tumor (ATT/RhT) of the central nervous system are defined, and abnormalities of chromosome 22 distinguish ATT/RhTs from PNETs, which typically display an i(17q) abnormality.
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Metastasis Stage, Adjuvant Treatment, and Residual Tumor Are Prognostic Factors for Medulloblastoma in Children: Conclusions From the Children's Cancer Group 921 Randomized Phase III Study
Paul M. Zeltzer,James M. Boyett,Jonathan L. Finlay,A. Leland Albright,L B Rorke,Jerrold M. Milstein,Jeffrey C. Allen,Kenneth R. Stevens,P Stanley,Hao Li,Jeffrey H. Wisoff,J. Russell Geyer,Patsy McGuire-Cullen,James A. Stehbens,Susan B. Shurin,Roger J. Packer +15 more
TL;DR: VCPplus XRT is a superior adjuvant combination compared with 8-in-1 chemotherapy plus XRT, and for patients with M0 tumors, residual tumor bulk (not extent of resection) is a predictor for PFS.
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The Childhood Cancer Survivor Study: A National Cancer Institute–Supported Resource for Outcome and Intervention Research
Leslie L. Robison,Gregory T. Armstrong,John D. Boice,Eric J. Chow,Stella M. Davies,Sarah S. Donaldson,Daniel M. Green,Sue Hammond,Anna T. Meadows,Ann C. Mertens,John J. Mulvihill,Paul C. Nathan,Joseph P. Neglia,Roger J. Packer,Preetha Rajaraman,Charles A. Sklar,Marilyn Stovall,Louise C. Strong,Yutaka Yasui,Lonnie K. Zeltzer +19 more
TL;DR: This ongoing study, which reflects the single most comprehensive body of information ever assembled on childhood and adolescent cancer survivors, provides a dynamic framework and resource to investigate current and future questions about childhood cancer survivors.
Journal ArticleDOI
Treatment of Children With Medulloblastomas With Reduced-Dose Craniospinal Radiation Therapy and Adjuvant Chemotherapy: A Children's Cancer Group Study
Roger J. Packer,Joel W. Goldwein,H. Stacy Nicholson,L. Gilbert Vezina,Jeffrey C. Allen,M. Douglas Ris,Karin M. Muraszko,Lucy B. Rorke,William M. Wara,Bruce H. Cohen,James M. Boyett +10 more
TL;DR: The results suggest that reduced-dose craniospinal radiation therapy and adjuvant chemotherapy during and after radiation is a feasible approach for children with nondisseminated medulloblastoma.