Roger Stupp

TL;DR: In patients with FL, the administration of 4 additional doses of rituximab at 8-week intervals significantly improves the EFS andCirculating normal B lymphocytes and immunoglobulin M plasma levels decreased for a significantly longer time after prolonged treatment, but the incidence of adverse events was not increased.

TL;DR: Assessment of classification by DNA methylation profiling and additional +7/−10 signatures appear to be promising as well and could be considered in the future following additional experience and validation.

TL;DR: This work presents a meta-analyses of the prophylactic and descriptive literature reviews that show clear trends in prognosis and pre-operatively diagnosed patients with atypical central giant cell granuloma have poorer prognosis after surgery than other models.

TL;DR: An exploratory subanalysis of the EORTC and NCIC data is undertaken to confirm or identify new prognostic factors for survival in adult patients with glioblastoma, derive nomograms that predict an individual patient's prognosis, and suggest stratification factors for future trials.

TL;DR: Although the relative contribution of the concomitant and the adjuvant chemotherapy, respectively, cannot be assessed, the early introduction of chemotherapy and the simultaneous administration with radiotherapy appear to be key for the improvement of outcome.