R
Rohan E. J. Beckwith
Researcher at University of Nottingham
Publications - 9
Citations - 1421
Rohan E. J. Beckwith is an academic researcher from University of Nottingham. The author has contributed to research in topics: Catalysis & Nucleophile. The author has an hindex of 4, co-authored 8 publications receiving 1290 citations. Previous affiliations of Rohan E. J. Beckwith include State University of New York System & University at Buffalo.
Papers
More filters
Journal ArticleDOI
Catalytic enantioselective C-H activation by means of metal-carbenoid-induced C-H insertion.
Journal ArticleDOI
Catalytic asymmetric reactions for organic synthesis: the combined C-H activation/siloxy-cope rearrangement.
TL;DR: Tetrakis(N-[4-dodecylbenzenesulfonyl]-(L)-prolinate) dirhodium-catalyzed decomposition of vinyldiazoacetates in the presence of allyl silyl ethers results in the formation of the direct C-H insertion product and the product derived from a combined C- H activation/siloxy-Cope rearrangement.
Journal ArticleDOI
Catalytic Enantioselective C—H Activation by Means of Metal—Carbenoid-Induced C—H Insertion
Journal ArticleDOI
Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy.
Simone Bonazzi,E. d’Hennezel,Rohan E. J. Beckwith,Lei Xu,Aleem Fazal,Anna Magracheva,Radha Ramesh,Artiom Cernijenko,Brandon Antonakos,Hyo-eun C. Bhang,Roxana Garcia Caro,Jennifer Cobb,Elizabeth Ornelas,Xiaolei Ma,Charles Wartchow,Matthew C. Clifton,Ry R. Forseth,Bethany Hughes Fortnam,Alfredo Csibi,Jennifer Tullai,Seth Carbonneau,Noel M. Thomsen,Jay F. Larrow,Barbara Chie-Leon,Dominik Hainzl,Yi Gu,Darlene Lu,Matthew J. Meyer,Dylan Alexander,Jacqueline Kinyamu-Akunda,Catherine Anne Sabatos-Peyton,Natalie A. Dales,Frédéric Zecri,Rishi K. Jain,Janine Shulok,Y. Karen Wang,Karin Briner,Jeffery A. Porter,John A. Tallarico,Jeffrey A. Engelman,Glenn Dranoff,James E. Bradner,Michael Visser,Jonathan M. Solomon +43 more
TL;DR: NVP-DKY709 as mentioned in this paper is a selective molecular glue degrader of IKZF2 that spares the degradation selectivity of cereblon (CRBN) binders.
Journal ArticleDOI
Chlorotrimethylsilane-mediated Michael addition reactions of chiral benzylic anions derived from η6-chromiumtricarbonyl complexes
TL;DR: The Michael addition of chiral organolithiums, resulting from benzylic metallation of certain η 6 -chromiumtricarbonyl complexes, to α,β-unsaturated ketones and esters, is strongly influenced by the presence of chlorotrimethylsilane.