scispace - formally typeset
R

Rohit Ramachandran

Researcher at Rutgers University

Publications -  141
Citations -  4515

Rohit Ramachandran is an academic researcher from Rutgers University. The author has contributed to research in topics: Granulation & Population. The author has an hindex of 37, co-authored 127 publications receiving 3755 citations. Previous affiliations of Rohit Ramachandran include Imperial College London & Massachusetts Institute of Technology.

Papers
More filters

Economic Analysis of Integrated Continuous and Batch Pharmaceutical Manufacturing

Spencer D. Schaber, +5 more
TL;DR: In this paper, the authors compared the costs of a dedicated continuous manufacturing process to synthesize an active pharmaceutical ingredient (API) and formulate it into tablets for a production scale of 2000 t of tablets per year, with raw material cost, production yield and API loading varied over broad ranges.
Journal ArticleDOI

Economic Analysis of Integrated Continuous and Batch Pharmaceutical Manufacturing: A Case Study

Spencer D. Schaber, +5 more
- 02 Aug 2011 - 
TL;DR: In this article, the authors compared the capital, operating, and overall costs of a dedicated continuous manufacturing process to synthesize an active pharmaceutical ingredient (API) and formulate it into tablets for a production scale of 2000 t of tablets per year.
Journal ArticleDOI

An integrated approach for dynamic flowsheet modeling and sensitivity analysis of a continuous tablet manufacturing process

Fani Boukouvala, +4 more
- 11 Jul 2012 - 
TL;DR: This work aims to identify the challenges in flowsheet model development and simulation for solid-based pharmaceutical processes and show its application and advantages for the integrated simulation and sensitivity analysis of two tablet manufacturing case studies: direct compaction and dry granulation.
Journal ArticleDOI

An engineering study on the enhanced control and operation of continuous manufacturing of pharmaceutical tablets via roller compaction.

Ravendra Singh, +2 more
- 15 Nov 2012 - 
TL;DR: Enhanced performance of critical quality attributes (CQAs) under closed-loop control compared to open-loop operation is demonstrated thus illustrating the potential of closed- loop feedback control in improving pharmaceutical manufacturing operations.
Journal ArticleDOI

System-wide hybrid MPC-PID control of a continuous pharmaceutical tablet manufacturing process via direct compaction.

Ravendra Singh, +2 more
- 01 Nov 2013 - 
TL;DR: Enhanced performance of critical quality attributes (CQAs) under the hybrid control scheme compared to only PID or MPC control schemes is demonstrated, illustrating the potential of a hybrid control schemes in improving pharmaceutical manufacturing operations.