R
Roland Beckmann
Researcher at Ludwig Maximilian University of Munich
Publications - 189
Citations - 15752
Roland Beckmann is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Ribosome & Eukaryotic Ribosome. The author has an hindex of 66, co-authored 164 publications receiving 12696 citations. Previous affiliations of Roland Beckmann include Free University of Berlin & Center for Integrated Protein Science Munich.
Papers
More filters
Journal ArticleDOI
Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Matthias Thoms,Robert Buschauer,Michael Ameismeier,Lennart Koepke,Timo Denk,Maximilian Hirschenberger,Hanna Kratzat,Manuel Hayn,Timur Mackens-Kiani,Jingdong Cheng,Jan Hendrik Straub,Christina M. Stürzel,Thomas Fröhlich,Otto Berninghausen,Thomas Becker,Frank Kirchhoff,Konstantin M. J. Sparrer,Roland Beckmann +17 more
TL;DR: Structural characterization of the inhibitory mechanism of Nsp1 may aid structure-based drug design against SARS-CoV-2 and effectively blocks retinoic acid–inducible gene I–dependent innate immune responses that would otherwise facilitate clearance of the infection.
Journal ArticleDOI
Structure of the 80S Ribosome from Saccharomyces cerevisiae—tRNA-Ribosome and Subunit-Subunit Interactions
Christian M. T. Spahn,Roland Beckmann,Roland Beckmann,Narayanan Eswar,Pawel A. Penczek,Andrej Sali,Günter Blobel,Joachim Frank,Joachim Frank,Joachim Frank +9 more
TL;DR: This analysis presents an exhaustive inventory of an eukaryotic ribosome at the molecular level, with mainly rRNA contributing to its molecular environment.
Journal ArticleDOI
Structures of the human and Drosophila 80S ribosome
Andreas M. Anger,Jean Paul Armache,Otto Berninghausen,Michael Habeck,Marion Subklewe,Daniel N. Wilson,Roland Beckmann +6 more
TL;DR: In this paper, the structure of metazoan 80S ribosomes with the translation factor eEF2, E-site transfer RNA and Stm1-like proteins has been determined.
Journal ArticleDOI
A new system for naming ribosomal proteins
Nenad Ban,Roland Beckmann,Jamie H. D. Cate,Jonathan D. Dinman,François Dragon,Steven R. Ellis,Denis L. J. Lafontaine,Lasse Lindahl,Anders Liljas,Jeffrey M. Lipton,Michael A. McAlear,Peter B. Moore,Harry F. Noller,Joaquin Ortega,Vikram Govind Panse,Venki Ramakrishnan,Christian M. T. Spahn,Thomas A. Steitz,Marek Tchórzewski,David Tollervey,Alan J. Warren,James R. Williamson,Daniel N. Wilson,Ada Yonath,Marat Yusupov +24 more
TL;DR: A system for naming ribosomal proteins is described, designed so that new names are similar enough to old names to be easily recognized, but are written in a format that unambiguously identifies them as 'new system' names.
Journal ArticleDOI
Structure of the signal recognition particle interacting with the elongation-arrested ribosome
Mario Halic,Thomas Becker,Martin R. Pool,Christian M. T. Spahn,Robert A. Grassucci,Robert A. Grassucci,Joachim Frank,Joachim Frank,Roland Beckmann +8 more
TL;DR: The model shows how the S domain of SRP contacts the large ribosomal subunit at the nascent chain exit site to bind the signal sequence, and that the Alu domain reaches into the elongation-factor-binding site of the ribosome, explaining its elongation arrest activity.