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Roland E. Schmieder

Researcher at University of Erlangen-Nuremberg

Publications -  780
Citations -  85811

Roland E. Schmieder is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Blood pressure & Essential hypertension. The author has an hindex of 97, co-authored 717 publications receiving 78138 citations. Previous affiliations of Roland E. Schmieder include Complutense University of Madrid & University of Regensburg.

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Safety, tolerability, and efficacy of a fixed-dose combination of olmesartan 40 mg and hydrochlorothiazide 12.5/25 mg in daily practice

TL;DR: The authors' data confirm randomized trial data concerning safe and efficient blood pressure reduction using a fixed-dose combination of olmesartan 40 mg and HCTZ 12.5/25 mg in a large, unselected patient population, independent of physical activity level.
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Aliskiren: a clinical profile

TL;DR: Aliskiren fulfils key criteria for a new antihypertensive agent, notably effective blood pressure lowering as monotherapy and combination therapy, 24-hour blood pressure control, safety and tolerability end-organ protective effects, minimal drug interaction and efficacy during long-term use.
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Renal endothelial effects of antihypertensive therapy.

TL;DR: No critically contributes to renal perfusion and there is evidence of reduced but also of unchanged NO bioavailability in the renal vasculature of patients with arterial hypertension both from protein expression and functional studies.
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Role of the angiotensin II type 2 receptor gene (+1675G/A) polymorphism on left ventricular hypertrophy and geometry in treated hypertensive patients

TL;DR: A genetic polymorphism in the angiotensin II type 2 receptor (AGTR2 +1675G/A) has been associated with left ventricular hypertrophy (LVH) but exhibits only a minor effect onleft ventricular geometry in women and none in men.