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Roland J. Siezen

Researcher at Radboud University Nijmegen

Publications -  167
Citations -  15882

Roland J. Siezen is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Lactococcus lactis & Genome. The author has an hindex of 66, co-authored 167 publications receiving 14956 citations. Previous affiliations of Roland J. Siezen include Netherlands Bioinformatics Centre & Radboud University Nijmegen Medical Centre.

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Journal ArticleDOI

Complete genome sequence of Lactobacillus plantarum WCFS1

Michiel Kleerebezem, +19 more
- 18 Feb 2003 - 
TL;DR: The 3,308,274-bp sequence of the chromosome of Lactobacillus plantarum strain WCFS1, a single colony isolate of strain NCIMB8826 that was originally isolated from human saliva, has been determined, and contains 3,052 predicted protein-encoding genes, suggesting that these genes form a lifestyle adaptation region in the chromosome.
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Subtilases: the superfamily of subtilisin-like serine proteases.

Roland J. Siezen, +1 more
- 01 Mar 1997 - 
TL;DR: Details of more than 100 new subtilases discovered in the past five years are summarized, and amino acid sequences of their catalytic domains are compared in a multiple sequence alignment.
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Characterization of the nisin gene cluster nisABTCIPR of Lactococcus lactis. Requirement of expression of the nisA and nisI genes for development of immunity

Oscar P. Kuipers, +3 more
- 01 Aug 1993 - 
TL;DR: Transcription analyses of several L. lactis strains indicated that an expression product of the nisA gene, together with NisR, is required for the activation of nisinA transcription, indicating that NisI plays a role in the immunity mechanism.
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Identification and characterization of the lantibiotic nisin Z, a natural nisin variant

John W. M. Mulders, +4 more
- 01 Nov 1991 - 
TL;DR: NMR studies of the natural nisin variant, which has been designated nisin Z, confirmed the His27Asn substitution and indicated that it has a similar structure to nisin.
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Epochal Evolution of GGII.4 Norovirus Capsid Proteins from 1995 to 2006

J. Joukje Siebenga, +6 more
- 15 Sep 2007 - 
TL;DR: The consistent association between the observed genetic findings and changes in epidemiology leads to the conclusion that population immunity plays a role in the epochal evolution of GGII.4 norovirus strains.