R
Roman Štukelj
Researcher at University of Ljubljana
Publications - 26
Citations - 4010
Roman Štukelj is an academic researcher from University of Ljubljana. The author has contributed to research in topics: Vesicle & Extracellular vesicle. The author has an hindex of 8, co-authored 23 publications receiving 2843 citations.
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Journal ArticleDOI
Biological properties of extracellular vesicles and their physiological functions
María Yáñez-Mó,Pia Siljander,Zoraida Andreu,Apolonija Bedina Zavec,Francesc E. Borràs,Edit I. Buzás,Krisztina Buzas,Krisztina Buzas,Enriqueta Casal,Francesco Cappello,Joana Carvalho,Joana Carvalho,Eva Colas,Anabela Cordeiro da Silva,Anabela Cordeiro da Silva,Stefano Fais,Juan M. Falcón-Pérez,Irene M. Ghobrial,Bernd Giebel,Mario Gimona,Mario Gimona,Michael W. Graner,Ihsan Gursel,Mayda Gursel,Niels H. H. Heegaard,Niels H. H. Heegaard,An Hendrix,Peter Kierulf,Katsutoshi Kokubun,Maja Kosanović,Veronika Kralj-Iglič,Eva-Maria Krämer-Albers,Saara Laitinen,Cecilia Lässer,Thomas Lener,Thomas Lener,Erzsébet Ligeti,Aija Linē,Georg Lipps,Alicia Llorente,Jan Lötvall,Mateja Manček-Keber,Antonio Marcilla,María Mittelbrunn,Irina Nazarenko,Esther N. M. Nolte-‘t Hoen,Tuula A. Nyman,Lorraine O'Driscoll,Mireia Olivan,Carla Oliveira,Carla Oliveira,Éva Pállinger,Hernando A. del Portillo,Hernando A. del Portillo,Jaume Reventós,Jaume Reventós,Marina Rigau,Eva Rohde,Eva Rohde,Marei Sammar,Francisco Sánchez-Madrid,Nuno Santarém,Nuno Santarém,Katharina Schallmoser,Katharina Schallmoser,Marie Stampe Ostenfeld,Willem Stoorvogel,Roman Štukelj,Susanne G. van der Grein,M. Helena Vasconcelos,M. Helena Vasconcelos,Marca H. M. Wauben,Olivier De Wever +72 more
TL;DR: A comprehensive overview of the current understanding of the physiological roles of EVs is provided, drawing on the unique EV expertise of academia-based scientists, clinicians and industry based in 27 European countries, the United States and Australia.
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Isolated microvesicles from peripheral blood and body fluids as observed by scanning electron microscope
Anita Mrvar-Brečko,Anita Mrvar-Brečko,Vid Šuštar,Vid Janša,Roman Štukelj,Rado Janša,Emir Mujagić,Peter Kruljc,Aleš Iglič,Henry Hägerstrand,Veronika Kralj-Iglič +10 more
TL;DR: This work presents scanning electronic microscope images of microvesicles isolated from blood, ascites, pleural fluid, cerebrospinal fluid, postoperative drainage fluid and chyloid fluid acquired from human and animal patients and indicates that methods of isolation and determination of the number ofmicrovesicles in the peripheral blood are to be elaborated and improved.
Journal ArticleDOI
Nanoparticles isolated from blood: a reflection of vesiculability of blood cells during the isolation process.
Vid Šuštar,Apolonija Bedina-Zavec,Roman Štukelj,Mojca Frank,Goran Bobojevic,Rado Janša,Eva Ogorevc,Peter Kruljc,Keriya Mam,Boštjan Šimunič,Mateja Manček-Keber,Roman Jerala,Blaž Rozman,Peter Veranič,Henry Hägerstrand,Veronika Kralj-Iglič +15 more
TL;DR: The results show that the contents of isolates reflect the properties of blood cells and their interaction with the surrounding solution (rather than representing only nanoparticles present in blood at sampling) which differ in different diseases and may therefore present a relevant clinical parameter.
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Effect of engineered TiO2 and ZnO nanoparticles on erythrocytes, platelet-rich plasma and giant unilamelar phospholipid vesicles
Metka Šimundić,Barbara Drasler,Vid Šuštar,Jernej Zupanc,Roman Štukelj,Darko Makovec,Deniz Erdogmus,Henry Hägerstrand,Damjana Drobne,Veronika Kralj-Iglič +9 more
TL;DR: Results indicate that TiO2 and ZnO EPs cause erythrocyte aggregation and could be potentially prothrombogenic, while ZNO could also cause membrane rupture.
Journal ArticleDOI
Effect of shear stress in the flow through the sampling needle on concentration of nanovesicles isolated from blood
Roman Štukelj,Karin Schara,Apolonija Bedina Zavec,Vid Šuštar,Manca Pajnič,Ljubiša Pađen,Judita Lea Krek,Veronika Kralj-Iglič,Anita Mrvar-Brečko,Rado Janša +9 more
TL;DR: The results are in favor of the hypothesis that a significant pool of nanovesicles in blood isolates is created during their harvesting, and the identity, shape, size and composition of NVs in isolates strongly depend on the technology of their harvesting.