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Ronald L. Wilder

Researcher at National Institutes of Health

Publications -  203
Citations -  42274

Ronald L. Wilder is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Arthritis & Rheumatoid arthritis. The author has an hindex of 74, co-authored 203 publications receiving 41223 citations. Previous affiliations of Ronald L. Wilder include Uniformed Services University of the Health Sciences & PAREXEL.

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Journal Article

The Sympathetic Nerve—An Integrative Interface between Two Supersystems: The Brain and the Immune System

TL;DR: The activation of SNS during an immune response might be aimed to localize the inflammatory response, through induction of neutrophil accumulation and stimulation of more specific humoral immune responses, although systemically it may suppress Th1 responses, and, thus protect the organism from the detrimental effects of proinflammatory cytokines and other products of activated macrophages.
Journal Article

Expression of Cyclooxygenase-1 and -2 in Human Colorectal Cancer

TL;DR: The data suggest that the enhanced expression of the COX-2 gene in Colon cancer tissues may contribute to the enhanced synthesis of prostaglandin E2 by the colon cancer tissues.
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The Pathophysiologic Roles of Interleukin-6 in Human Disease

TL;DR: What makes interleukin-6 particularly interesting to physicians is its marked pleiotropy and its involvement not only in inflammation but in the regulation of endocrine and metabolic functions.
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Inflammatory mediator-induced hypothalamic-pituitary-adrenal axis activation is defective in streptococcal cell wall arthritis-susceptible Lewis rats

TL;DR: Findings support the concept that susceptibility of LEW/N rats to SCW arthritis is related to defective HPA axis responsiveness to inflammatory and other stress mediators and that resistance of F344/N Rats to SCw arthritis is regulated by an intact HPAaxis-immune system feedback loop.