R
Roujian Lu
Researcher at Chinese Center for Disease Control and Prevention
Publications - 23
Citations - 6824
Roujian Lu is an academic researcher from Chinese Center for Disease Control and Prevention. The author has contributed to research in topics: Human metapneumovirus & Coronavirus. The author has an hindex of 11, co-authored 23 publications receiving 5541 citations. Previous affiliations of Roujian Lu include University of Alabama at Birmingham.
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Journal ArticleDOI
Detection of SARS-CoV-2 in Different Types of Clinical Specimens.
TL;DR: Results of PCR and viral RNA testing for SARS-CoV-2 in bronchoalveolar fluid, sputum, feces, blood, and urine specimens from patients with COVID-19 infection in China are described to identify possible means of non-respiratory transmission.
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In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Xueting Yao,Fei Ye,Miao Zhang,Cheng Cui,Baoying Huang,Peihua Niu,Xu Liu,Li Zhao,Erdan Dong,Chunli Song,Siyan Zhan,Roujian Lu,Haiyan Li,Wenjie Tan,Dongyang Liu +14 more
TL;DR: It is proposed that the immunomodulatory effect of hydroxychloroquine also may be useful in controlling the cytokine storm that occurs late-phase in critically ill SARS-CoV-2 infected patients.
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Characterization of human coronavirus etiology in Chinese adults with acute upper respiratory tract infection by real-time RT-PCR assays.
Roujian Lu,Xiaoyan Yu,Xiaoyan Yu,Wen Wang,Xijie Duan,Ling-lin Zhang,Weimin Zhou,Jin Xu,Lingjie Xu,Qin Hu,Qin Hu,Jianxin Lu,Li Ruan,Zhong Wang,Wenjie Tan +14 more
TL;DR: All 4 non-SARS-associated HCoVs were more frequently detected by real-time RT-PCR assay in adults with URTI in Beijing and HCoV-229E led to the most prevalent infection.
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Etiology and clinical characterization of respiratory virus infections in adult patients attending an emergency department in Beijing.
Xiaoyan Yu,Xiaoyan Yu,Roujian Lu,Zhong Wang,Na Zhu,Wen Wang,Druce Julian,Birch Chris,Jianxin Lv,Wenjie Tan,Wenjie Tan +10 more
TL;DR: The pattern of RV involvement in adults with ARTIs attending an ED in China differs from that previously reported, and the high prevalence of viruses (PIC, FluA, HCoVs and ADV) reported here strongly highlight the need for the development of safe and effective therapeutic approaches for these viruses.
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Arrestin Serves as a Molecular Switch, Linking Endogenous α2-Adrenergic Receptor to SRC-dependent, but Not SRC-independent, ERK Activation
TL;DR: The data demonstrate that the endogenous α2AAR evokes ERK phosphorylation through both a SRC-dependent and a Src-independent pathway, both of which are G protein dependent and converge on the Ras-Raf-MEK pathway.