R
Rui Liu
Researcher at University of Michigan
Publications - 7
Citations - 3406
Rui Liu is an academic researcher from University of Michigan. The author has contributed to research in topics: Cancer & Stem cell. The author has an hindex of 3, co-authored 6 publications receiving 3250 citations.
Papers
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Journal ArticleDOI
Phenotypic characterization of human colorectal cancer stem cells
Piero Dalerba,Scott J. Dylla,In-Kyung Park,Rui Liu,Xinhao Wang,Robert W. Cho,Timothy Hoey,Austin L. Gurney,Emina Huang,Diane M. Simeone,Andrew A. Shelton,Giorgio Parmiani,Chiara Castelli,Michael F. Clarke +13 more
TL;DR: The results validate the stem cell working model in human CRC and provide a highly robust surface marker profile for CRC stem cell isolation.
Journal ArticleDOI
The Prognostic Role of a Gene Signature from Tumorigenic Breast-Cancer Cells
Rui Liu,Xinhao Wang,Grace Y. Chen,Piero Dalerba,Piero Dalerba,Austin L. Gurney,Timothy Hoey,Gavin Sherlock,John Lewicki,Kerby Shedden,Michael F. Clarke,Michael F. Clarke +11 more
TL;DR: The gene-expression profile of CD44+CD24-/low tumorigenic breast-cancer cells with that of normal breast epithelium was compared to generate a 186-gene "invasiveness" gene signature (IGS), which was evaluated for its association with overall survival and metastasis-free survival in patients with breast cancer or other types of cancer.
Journal ArticleDOI
Dysregulated gene expression networks in human acute myelogenous leukemia stem cells
Ravindra Majeti,Michael W. Becker,Qiang Tian,Qiang Tian,Tsung Lu Michael Lee,Tsung Lu Michael Lee,Xiaowei Yan,Rui Liu,Jung-Hsien Chiang,Leroy Hood,Michael F. Clarke,Irving L. Weissman +11 more
TL;DR: This study demonstrates that combining global gene expression analysis with detailed annotated pathway resources applied to highly enriched normal and malignant stem cell populations, can yield an understanding of the critical pathways regulating cancer stem cells.
Patent
Compositions et methodes de traitement et de diagnostic du cancer
Michael F Clarke,Rui Liu +1 more
TL;DR: In this paper, the presente invention concerne des compositions and methodes for le traitement, la caracterisation, and le diagnostic du cancer, concurring des profils d'expression genique associes a des cellules souches de tumeurs solides.