Runzhi Xia

TL;DR: 3D printing technology presents new potential for treating complex hip joint disease and could improve the surgeon's efficiency in the operating room, shorten operative times, and reduce exposure to radiation.

TL;DR: Titanium and titanium alloys are widely used in orthopedic implants and modifying the nanotopography provides a new strategy to improve osseointegration of titanium substrates, and it is concluded that TiO2 nanotubes facilitated the osteogenic differentiation of MSCs, and this ability was enhanced with the increasing diameter of thenanotubes.

TL;DR: The present study showed that mechanical strain promoted cell proliferation, spreading and increased vinculin expression of MSCs on the TiO2 nanotubes substrate, and enhanced the ALP activity and osteogenesis genes expression such as Runx2, BSP, ALP, OPN and OCN.

TL;DR: The “Skywalker” system has good osteotomy accuracy, can achieve the planned angles well, and is expected to assist surgeons in performing accurate bone cuts and reconstructing planned lower limb alignments in the relevant clinical applications in future.

TL;DR: Results showed that F-actin mediated nanotube-induced cell differentiation through promoting the expression of GCN5 and enhancing the function ofGCN5 was a key regulator of the osteogenic differentiation of BMSCs induced by TiO2 nanotubes as a downstream mediated osteogenesis of F-actsin.