Author
Ruqin Shen
Other affiliations: Jinan University
Bio: Ruqin Shen is an academic researcher from Nanjing University. The author has contributed to research in topics: Intestinal permeability & Hormone metabolism. The author has an hindex of 2, co-authored 3 publications receiving 40 citations. Previous affiliations of Ruqin Shen include Jinan University.
Papers
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TL;DR: Gut microbiota analysis found that the combined exposure of MPs and DEHP also caused alterations in gut microbiota composition, especially some energy metabolism and immune function related bacteria were significantly changed in the relative abundance.
134 citations
TL;DR: Compared with virgin MPs and PAEs alone, PAE-contaminated MPs induced enhanced reproductive toxicities manifested by greater alterations in sperm physiology and spermatogenesis, which provide valuable insights into the mechanism of combined toxicity of MPs and other pollutants.
68 citations
13 Aug 2021
3 citations
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TL;DR: A growing body of evidence showing that nano- and microplastic exposure disturbs the gut microbiota and critical intestinal functions is brought together, showing that such effects may promote the development of chronic immune disorders.
Abstract: Together with poor biodegradability and insufficient recycling, the massive production and use of plastics have led to widespread environmental contamination by nano- and microplastics. These particles accumulate across ecosystems - even in the most remote habitats - and are transferred through food chains, leading to inevitable human ingestion, that adds to the highest one due to food processes and packaging. The present review aimed at providing a comprehensive overview of current knowledge regarding the effects of nano- and microplastics on intestinal homeostasis. We conducted a literature search focused on the in vivo effects of nano- and microplastics on gut epithelium and microbiota, as well as on immune response. Numerous animal studies have shown that exposure to nano- and microplastics leads to impairments in oxidative and inflammatory intestinal balance, and disruption of the gut’s epithelial permeability. Other notable effects of nano- and microplastic exposure include dysbiosis (changes in the gut microbiota) and immune cell toxicity. Moreover, microplastics contain additives, adsorb contaminants, and may promote the growth of bacterial pathogens on their surfaces: they are potential carriers of intestinal toxicants and pathogens that can potentially lead to further adverse effects. Despite the scarcity of reports directly relevant to human, this review brings together a growing body of evidence showing that nano- and microplastic exposure disturbs the gut microbiota and critical intestinal functions. Such effects may promote the development of chronic immune disorders. Further investigation of this threat to human health is warranted.
193 citations
TL;DR: In this article, a review article summarizes different aging processes of microplastics and subsequent effects on the adsorption of pollutants, the leaching of additives, and the toxicity of MPs.
141 citations
TL;DR: In this article , a review article summarizes different aging processes of microplastics and subsequent effects on the adsorption of pollutants, the leaching of additives, and the toxicity of MPs.
140 citations
TL;DR: This review provided the latest research information on the differences in toxicity between MPs and NPs in the digestive system, reproductive system and nervous system, and explored the possible reasons for differences for the first time.
131 citations
TL;DR: Wang et al. as discussed by the authors investigated airborne microplastics in indoor and outdoor environments from urban and rural areas of a coastal city in eastern China and found that the larger MP size fractions contained a higher proportion of fibers whereas the smaller size fractions were nearly exclusively composed of fragments.
96 citations