R
Ryne C. Ramaker
Researcher at University of Alabama at Birmingham
Publications - 39
Citations - 927
Ryne C. Ramaker is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Gene & Exome. The author has an hindex of 15, co-authored 37 publications receiving 634 citations.
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Journal ArticleDOI
Post-mortem molecular profiling of three psychiatric disorders
Ryne C. Ramaker,Kevin M. Bowling,Brittany N. Lasseigne,Megan Hastings Hagenauer,Andrew A. Hardigan,Nicholas S. Davis,Jason Gertz,Preston M. Cartagena,David M. Walsh,Marquis P. Vawter,Edward G. Jones,Alan F. Schatzberg,Jack D. Barchas,Stanley J. Watson,Blynn G. Bunney,Huda Akil,William E. Bunney,Jun Li,Sara J. Cooper,Richard M. Myers +19 more
TL;DR: A high-confidence set of independently validated genes differentially expressed between schizophrenia and control patients in the anterior cingulate cortex are highlighted and integrated transcriptional changes with untargeted metabolite profiling are integrated.
Journal ArticleDOI
Cancer cell proliferation is inhibited by specific modulation frequencies.
Jacquelyn W. Zimmerman,Michael J. Pennison,Ivan A. Brezovich,Nengjun Yi,Celeste T. Yang,Ryne C. Ramaker,Devin Absher,Richard M. Myers,Niels Kuster,Filomena Costa,Alexandre Barbault,Boris Pasche +11 more
TL;DR: These findings uncover a novel mechanism controlling the growth of cancer cells at specific modulation frequencies without affecting normal tissues, which may have broad implications in oncology.
Journal ArticleDOI
Occupancy maps of 208 chromatin-associated proteins in one human cell type.
E. Christopher Partridge,Surya B. Chhetri,Surya B. Chhetri,Jeremy W. Prokop,Ryne C. Ramaker,Camden Jansen,Say-Tar Goh,Mark Mackiewicz,Kimberly M. Newberry,Laurel A. Brandsmeier,Sarah Meadows,C. Luke Messer,Andrew A. Hardigan,Candice J. Coppola,Emma C. Dean,Shan Jiang,Daniel Savic,Ali Mortazavi,Barbara J. Wold,Richard M. Myers,Eric M. Mendenhall +20 more
TL;DR: Data and analyses from chromatin immunoprecipitation followed by high-throughput sequencing (ChIP–seq) experiments using the human HepG2 cell line are presented, providing a comprehensive catalogue of the transcription factor landscape and gene regulatory networks in these cells.
Journal ArticleDOI
RNA sequencing of pancreatic adenocarcinoma tumors yields novel expression patterns associated with long-term survival and reveals a role for ANGPTL4.
Marie K. Kirby,Ryne C. Ramaker,Jason Gertz,Nicholas S. Davis,Bobbi E Johnston,Patsy G. Oliver,Katherine C. Sexton,Edward W Greeno,John D. Christein,Martin J. Heslin,James Posey,William E. Grizzle,Selwyn M. Vickers,Donald J. Buchsbaum,Sara J. Cooper,Richard M. Myers +15 more
TL;DR: Pancreatic adenocarcinoma patients have low survival rates due to late‐stage diagnosis and high rates of cancer recurrence even after surgical resection, and it is important to understand the molecular characteristics associated with survival differences.
Journal ArticleDOI
Genomic regulation of invasion by STAT3 in triple negative breast cancer.
Joy M. McDaniel,Katherine E. Varley,Jason Gertz,Daniel Savic,Brian S. Roberts,Sarah K. Bailey,Lalita A. Shevde,Ryne C. Ramaker,Brittany N. Lasseigne,Marie K. Kirby,Kimberly M. Newberry,E. Christopher Partridge,Angela Jones,Braden E. Boone,Shawn Levy,Patsy G. Oliver,Katherine C. Sexton,William E. Grizzle,Andres Forero,Donald J. Buchsbaum,Sara J. Cooper,Richard M. Myers +21 more
TL;DR: Novel gene signatures directly regulated by STAT3 are discovered that were enriched for processes involving inflammation, immunity, and invasion in TNBC, suggesting therapies targeting STAT3 may be important for preventing TNBC metastasis.