S. A. Serkov

Bio: S. A. Serkov is an academic researcher from Russian Academy of Sciences. The author has contributed to research in topics: Chemistry & Triazine. The author has an hindex of 4, co-authored 12 publications receiving 55 citations.

An effective one-pot access to polynuclear dispiroheterocyclic structures comprising pyrrolidinyloxindole and imidazothiazolotriazine moieties via a 1,3-dipolar cycloaddition strategy.

Abstract: An effective and highly regio- and diastereoselective one-pot method for the synthesis of new polynuclear dispiroheterocyclic systems with five stereogenic centers (dispiro[imidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazine-6,3′-pyrrolidine-2′,3′′-indoles]) comprising pyrrolidinyloxindole and imidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazine moieties has been developed. The method relies on a 1,3-dipolar cycloaddition of azomethine ylides generated in situ from isatin derivatives and sarcosine to 6-benzylideneimidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazine-2,7-diones.

Synthesis, S-alkylation, and fungicidal activity of 4-(benzylideneamino)thioglycolurils

Abstract: A series of 1,3-disubstituted 4-benzylideneamino-5-thioxohexahydroimidazo[4,5-d]imidazol-2(1H)-ones (thioglycolurils) was synthesized via the reaction of 5,7-disubstituted 3-thioxoperhydroimidazo[4,5-e]-1,2,4-triazin-6-ones with hydroxy-, alkoxy-, and fluorocontaining benzaldehyde derivatives. An alkylation of the obtained thioglycolurils with methyl iodide or 4-bromobenzyl bromide provided the corresponding 6-benzylideneamino-5-alkylsulfanyl-3,3a,6,6a-tetrahydroimidazo[4,5-d]imidazol-2(1H)-ones. The fungicidal activity of some synthesized compounds against pathogens causing diseases of agricultural crops was studied.

Synthesis of New Imidazo[4,5-e][1,3]thiazolo-[3,2-b][1,2,4]triazine Derivatives

Abstract: Previously unknown (Z)-6-aryl(hetaryl)methylidene derivatives of imidazo[4,5-e][1,3]thiazolo[3,2-b]-[1,2,4]triazine-2,7-diones were synthesized by aldol-crotonic condensation of imidazo[4,5-e]-[1,3]thiazolo[3,2-b][1,2,4]triazine-2,7-diones with aromatic or heteroaromatic aldehydes, or by three-component condensation of imidazo[4,5-e][1,2,4]triazine-3-thione, bromoacetic acid, and aldehyde.

Sulfamic acid and N -alkylsulfamates in the synthesis of nitro derivatives of guanidine and aminofurazan

Abstract: TheN-nitro derivatives of the products of the condensation of formaldehyde with sulfamic acid derivatives and guanidine, nitroguanidine, 3,4-diaminofurazan, and 3-amino-4-methylfurazan have been synthesized.

Monocyclic furazans and furoxans

Abstract: Publisher Summary This chapter covers the chemistry of monocyclic furazans and furoxans. The aim is to present a general picture of more than a century of development in this field. It focuses more on the reactivity of the side-chain functional groups than on the ring synthesis. A liberal selection of examples for preparations and reactions is offered. Because of the enormous amount of literature no exhaustive coverage of this field is intended. The chapter reviews that the chemistry of furazans and furoxans has been the subject of intensive investigations over the years. There has been a substantial increase in synthetic manipulations of substituents attached to these ring systems. Additionally, there are a number of publications that deal with the incorporation of the heterocyclic rings into more complex molecules.

A study of N-trinitroethyl-substituted aminofurazans: high detonation performance energetic compounds with good oxygen balance

Abstract: Two energetic N-trinitroethyl-substituted aminofurazans 11 and 12, as well as nitramine 13 (the N-nitration product of 12) were synthesized. All the compounds were well characterized by NMR spectra, IR spectroscopy, elemental analysis, differential scanning calorimetry (DSC) and thermogravimetric analysis (TG). Their structures were further confirmed by X-ray diffraction studies, which show favorable densities (1.82–1.87 g cm−3). Interestingly, they exhibit good thermal stability (Tdec = 159–230 °C), acceptable oxygen balance (−15.31%–0) and high positive heats of formation (268–1259.5 kJ mol−1). In addition, the performance calculations gave detonation pressures and velocities for the furazan derivatives in the range of 35.4–40.8 GPa and 8900–9486 m s−1, respectively. Furthermore, nitramine 13 (nitrate product of 12), having an oxygen balance of zero, exhibits outstanding detonation properties (ΔfHm, 1259.5 kJ mol−1; D, 9486 m s−1; P, 40.8 GPa), which could be used as a high detonation performance energetic material.