S
S. Andrew Josephson
Researcher at University of California, San Francisco
Publications - 206
Citations - 5159
S. Andrew Josephson is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Medicine & Public health. The author has an hindex of 33, co-authored 187 publications receiving 4102 citations. Previous affiliations of S. Andrew Josephson include American Medical Association & University of California.
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Journal ArticleDOI
Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis
Michael R. Wilson,Hannah A. Sample,Kelsey C. Zorn,Shaun Arevalo,Guixia Yu,John Neuhaus,Scot Federman,Doug Stryke,Benjamin Briggs,Charles Langelier,Amy C. Berger,Vanja C. Douglas,S. Andrew Josephson,Felicia C. Chow,Brent D. Fulton,Joseph L. DeRisi,Jeffrey M. Gelfand,Samia N. Naccache,Jeffrey M. Bender,Jennifer Dien Bard,Jamie A. Murkey,Magrit Carlson,Paul M. Vespa,Tara Vijayan,Paul R Allyn,Shelley Campeau,Romney M. Humphries,Jeffrey D. Klausner,Czarina Ganzon,Fatemeh Memar,Nicolle Anne Ocampo,Lara Zimmermann,Stuart H. Cohen,Christopher R. Polage,Roberta L. DeBiasi,Barbara Haller,Ronald H. Dallas,Gabriela Maron,Randall T. Hayden,Kevin Messacar,Samuel R. Dominguez,Steve Miller,Charles Y. Chiu +42 more
TL;DR: Routine microbiologic testing is often insufficient to detect all neuroinvasive pathogens, so metagenomic NGS of CSF obtained from patients with meningitis or encephalitis improved diagnosis of neurologic infections and provided actionable information in some cases.
Journal ArticleDOI
Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing.
Michael R. Wilson,Brian D. O’Donovan,Jeffrey M. Gelfand,Hannah A. Sample,Felicia C. Chow,John P. Betjemann,Maulik P. Shah,Megan B. Richie,Mark P. Gorman,Rula A. Hajj-Ali,Leonard H. Calabrese,Kelsey C. Zorn,Eric D. Chow,John E. Greenlee,John E. Greenlee,Jonathan H Blum,Gary Green,Lillian M. Khan,Debarko Banerji,Chaz Langelier,Chloe Bryson-Cahn,Whitney E. Harrington,Whitney E. Harrington,Jairam R Lingappa,Niraj M. Shanbhag,Ari J. Green,Bruce J. Brew,Bruce J. Brew,Ariane Soldatos,Luke Strnad,Sarah B Doernberg,Cheryl A. Jay,Vanja C. Douglas,S. Andrew Josephson,Joseph L. DeRisi +34 more
TL;DR: Diverse microbial pathogens were identified by mNGS in the CSF of patients with diagnostically challenging subacute or chronic meningitis, including a case of subarachnoid neurocysticercosis that defied diagnosis for 1 year, and the first reported case of CNS vasculitis caused by Aspergillus oryzae.
Journal ArticleDOI
National Stroke Association guidelines for the management of transient ischemic attacks.
S. Claiborne Johnston,Mai N. Nguyen-Huynh,Miriam E. Schwarz,Kate Fuller,Christina E Williams,S. Andrew Josephson,Graeme J. Hankey,Robert G. Hart,Steven R. Levine,José Biller,Robert D. Brown,Ralph L. Sacco,L. Jaap Kappelle,Peter J. Koudstaal,Julien Bogousslavsky,Louis R. Caplan,Jan van Gijn,Ale Algra,Peter M. Rothwell,Harold P. Adams,Gregory W. Albers +20 more
TL;DR: This work sought to create comprehensive, unbiased, evidence‐based guidelines for the management of patients with transient ischemic attacks.
Journal ArticleDOI
CXCL13 plus interleukin 10 is highly specific for the diagnosis of CNS lymphoma
James L. Rubenstein,Valerie S. Wong,Cigall Kadoch,Hua Xin Gao,Ramon F. Barajas,Lingjing Chen,S. Andrew Josephson,Brian J. Scott,Vanja C. Douglas,Mekhala Maiti,Lawrence D. Kaplan,Patrick A. Treseler,Soonmee Cha,Jimmy Hwang,Paola Cinque,Jason G. Cyster,Clifford A. Lowell +16 more
TL;DR: It is demonstrated for the first time that elevated CXCL13 concentration in cerebrospinal fluid (CSF) is prognostic and that CXC chemokine ligand and IL-10 mediate chemotaxis of lymphoma cells isolated from CNS lymphoma lesions.
Journal ArticleDOI
Voltage-gated potassium channel autoimmunity mimicking creutzfeldt-jakob disease.
Michael D. Geschwind,K. Meng Tan,Vanda A. Lennon,Ramon F. Barajas,Aissa Haman,Christopher J. Klein,S. Andrew Josephson,Sean J. Pittock +7 more
TL;DR: Serologic evaluation for markers of neurologic autoimmunity, including VGKC autoantibodies, may be warranted in suspected CJD cases.