S
S Gunasekaran
Researcher at Christian Medical College & Hospital
Publications - 33
Citations - 601
S Gunasekaran is an academic researcher from Christian Medical College & Hospital. The author has contributed to research in topics: Pancreatic islets & Transplantation. The author has an hindex of 11, co-authored 30 publications receiving 552 citations. Previous affiliations of S Gunasekaran include Texas Tech University Health Sciences Center & VIT University.
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Journal Article
Antidiabetic activity of Aloe vera and histology of organs in streptozotocin-induced diabetic rats
TL;DR: In diabetic rats and diabetic rats fed with A. vera, no change was noticed in the kidney and stomach, while in streptozotocin-induced diabetic rats, the fasting plasma glucose levels were reduced to normal and body weight was found to be increased.
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Effect of streptozotocin on the ultrastructure of rat pancreatic islets
TL;DR: It is concluded that the 30‐mg/kg body weight STZ produces mild changes while 50 mg/kg proves to be fatal, while STZ at 40 mg/ kg has a moderate effect on plasma glucose as well as on the islets of Langerhans at a cellular level.
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Improvement of Insulin Secretion and Pancreatic β-cell Function in Streptozotocin-induced Diabetic Rats Treated with Aloe vera Extract
TL;DR: A. vera extract exerts antidiabetic effects by improving insulin secretion and pancreatic β-cell function by restoring pancreatic islet mass in STZ-induced diabetic Wistar rats.
Journal Article
Anti-diabetic effect of Costus pictus leaves in normal and streptozotocin-induced diabetic rats
TL;DR: It is evident that the leaves of C. pictus have antidiabetic effect and must be considered as a potential candidate for future studies on diabetes mellitus.
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Human islet mass, morphology, and survival after cryopreservation using the Edmonton protocol
Priya Miranda,Viswanathan Mohan,Sekhar Ganthimathy,Ranjit Mohan Anjana,S Gunasekaran,Venkatachalam Thiagarajan,Thomas A. Churchill,Tatsuya Kin,A. M. James Shapiro,Jonathan R. T. Lakey +9 more
TL;DR: With an increasing culture duration although the physical integrity was retained there was an increasing loss of cohesivity both at light microscopic and at ultrastructure level regardless of the protocols used, indicating the need for more optimal cryopreservation and culture techniques.