S. Inbasekaran

Bio: S. Inbasekaran is an academic researcher from Central Leather Research Institute. The author has contributed to research in topics: Silver nanoparticle & Voltage regulator. The author has an hindex of 2, co-authored 5 publications receiving 20 citations.

Fabrication of novel biofibers by coating silk fibroin with chitosan impregnated with silver nanoparticles.

Abstract: Nanoparticle based agents often applied as coatings on biomaterials have shown promise in delivering the improved sterility against variety of microbes. In the present study, silk fibers (SF) were coated with chitosan impregnated with silver nanoparticles (Ag-C-SF). These Ag-C-SF fibers were characterized using scanning electron microscopy (SEM) with energy dispersive X-ray analysis, atomic force microscopy (AFM), Infra Red spectroscopy, Thermogravimetric Analysis and Microbiological assay techniques. AFM studies have confirmed the nano sized silver particles in chitosan solution; SEM pictures have exhibited the coating of chitosan along with silver nanoparticles on the silk fibroin. The modified fibers have also shown anti-microbial activity and improved thermal stability. The Ag-C-SF fibers may be explored as wound dressing and tendon reconstruction material in future.

Nanoparticle analysis for various medicinal drugs and human body saliva at macromolecular level

Abstract: The spectral bio-diagnosis of normal human body saliva sample shows the following functional compounds and it is related to various proteins and enzymes. Because of the presence of water in the saliva sample, the hydroxyl group is observed in the form of O–H at 3,305 cm−1, because of the presence of lipids, the functional group C–H is obtained from 2,928 to 2,856 cm−1, due to the presence of amide-I in the form of C=N and C=C obtained at 1,658 cm−1, the proteins are exhibited. Due to the presence of aliphatic CH2, the Lipids, Adenine, Cytosine, Collagen are observed at 1,455 cm−1, because of the presence of Carbohydrates, Phospholipids, Nucleic acids, the functional groups C=O and P=O from 1,159 to 1,064 cm−1 are exhibited. Due to the presence of Phenylalanine, Tyrosine, Cystine and Hydroxyapatite C–C twist, C–C stretch, C–S stretch and PO42− are observed at 748 and 483 cm−1. Silver nanoparticle has attracted considerable interest due to their extensive applicability in various areas such as electronics, catalysis, chemistry, energy and medicine. To study the opto-electronics properties of the samples, it was mixed with silver nanoparticles and characterized.

Biomedical Optical spectroscopy techniques for Diagnosis of Human saliva sample

Abstract: Fourier Transform Infrared Spectroscopy (FTIR) used for biomedical diagnosis of human saliva sample. Saliva is taken for experimental analysis from a normal person and also from a Gastric problem related patient. The spectral bio-diagnosis of normal human saliva sample shows the following vibrational functional groups O-H at 3305 cm-1, C-H from 2928 to 2856 cm-1, C=N and C=C obtained at 1658 cm-1, C-H bend at 1455 cm-1, C=S and C-C from 1159 to 1064 cm-1, C-H out of plane bend at 748 cm-1 and 483 cm-1 assigned for C-H deformation.

Novel design of low voltage DC source for bio nano diagnostic applications

Abstract: This paper aims designing prototype power supply for Nano biomedical applications in existing hospital industry. So far only the power supplies are designed using more number of passive components such as resistors, capacitors and inductors. But we have introduced a novel technique using silver nano particles to impregnate on the collagen sheet, deposited on electrode by electrodepositing method, it produces constant DC power supply voltage of 12 volts or 9 volts for biomedical diagnostic applications. Fourier Transform Infrared Spectroscopy spectrum of chitosan-hydroxyapatite composite film shows the characteristic peaks of chitosan and hydroxyapatite. The free ammonia groups are shown at 1637 cm -1 .The -CH 2 -CH 2 -vibration were observed at 2920 cm -1 .

WAN enabled super system for Nano-biomaterials packages for bio-products and bio-materials Scientists

Abstract: Recently, in India, many technologies are emerging, one among them is bio-products fabricated using T-CAD simulation software package and also using Virtual carbon nano tube (V-CNT) technology. The properties of biomaterials depend on the materials used in the process, their composition, pH, temperature, concentration etc. Based on the raw materials and the conditions applied, the physico-chemicals properties of the biomaterials are varied. This research paper discussed about the super system based wide area network [SSBWAN] technology for biomaterial researchers and users using information technology. It provides basic information and advanced technologies for users. This software can be multilingual so as to benefit scientists, technicians, researchers, students and clients and the web can be accessed easily using internet. This is developed using advanced software tools such as T-CAD, Virtual CNT, MySQL, PHP and Multimedia. This software provides all information regarding the processing of bio materials and it is very essential tool for biomaterial scientists and research scholars.

Nanoparticles for Tendon Healing and Regeneration: Literature Review.

Abstract: Tendon injuries are commonly met in the emergency department. Unfortunately, tendon tissue has limited regeneration potential and usually the consequent formation of scar tissue causes inferior mechanical properties Nanoparticles could be used in different way to improve tendon healing and regeneration, ranging from scaffolds manufacturing (increasing the strength and endurance or anti-adhesions, anti-microbial and anti-inflammatory properties) to gene therapy. This paper aims to summarize the most relevant studies showing the potential application of nanoparticles for tendon tissue regeneration

Silk Polymers and Nanoparticles: A Powerful Combination for the Design of Versatile Biomaterials.

Abstract: Silk fibroin (SF) is a natural protein largely used in the textile industry but also in biomedicine, catalysis, and other materials applications. SF is biocompatible, biodegradable, and possesses high tensile strength. Moreover, it is a versatile compound that can be formed into different materials at the macro, micro- and nano-scales, such as nanofibers, nanoparticles, hydrogels, microspheres, and other formats. Silk can be further integrated into emerging and promising additive manufacturing techniques like bioprinting, stereolithography or digital light processing 3D printing. As such, the development of methodologies for the functionalization of silk materials provide added value. Inorganic nanoparticles (INPs) have interesting and unexpected properties differing from bulk materials. These properties include better catalysis efficiency (better surface/volume ratio and consequently decreased quantify of catalyst), antibacterial activity, fluorescence properties, and UV-radiation protection or superparamagnetic behavior depending on the metal used. Given the promising results and performance of INPs, their use in many different procedures has been growing. Therefore, combining the useful properties of silk fibroin materials with those from INPs is increasingly relevant in many applications. Two main methodologies have been used in the literature to form silk-based bionanocomposites: in situ synthesis of INPs in silk materials, or the addition of preformed INPs to silk materials. This work presents an overview of current silk nanocomposites developed by these two main methodologies. An evaluation of overall INP characteristics and their distribution within the material is presented for each approach. Finally, an outlook is provided about the potential applications of these resultant nanocomposite materials.

Methods of making silver nanoparticles and their applications

Abstract: Disclosed herein is a method of making silver nanoparticles using an ascorbic acid derivative or an alpha-hydroxyl carboxylic acid derivative as a reducing agent. The silver nanoparticles may be coated onto micro particles, embedded in hydrogel particles or coated with polysaccharide. The silver nanoparticles may be used in a wound dressing, a bandage, a fungal treatment product, a deodorant, a floss product, a toothpick, a dietary supplement, dental X-ray, a mouthwash, a toothpaste, acne or wound treatment product, skin scrub, and skin defoliate agent.