Sabah H. El-Ghaiesh

TL;DR: This study is the first to highlight that the neuroprotective role of MTF is mediated through activation of AMPK-FOXO3 signaling and inhibition of the proangiogenic factor, VEGF.

TL;DR: Results highlighted, for the first time, the neuronal protective effect for CARB in diabetic retina, which is mediated, at least in part, by activation of the NGF/PI3K/Akt/mTOR pathway.

TL;DR: Data from this study documented the beneficial role of RB in diminishing weight gain, improving the inflammatory perturbations and energy expenditure in HF diet fed rats, suggesting RB might be a promising candidate for obesity.

TL;DR: Hormonal replacement therapy with regular monitoring of the patients represents a potential therapeutic strategy while avoiding opioids in patients with guaranteed long therapeutic exposure and switching to using low‐dose naltrexone as alternative represents a possible prophylactic measure to ensure therapeutic compliance and secure a good life quality of patients.

TL;DR: The data presented herein supported an anti-inflammatory role of levetiracetam in diabetic retinopathy, however, further clinical studies may be warranted to confirm the effectiveness and safety ofLevetir acetam in DR patients.