Sabine Hoffmann

TL;DR: It is suggested that identically designed RCTs conducted in different parts of the world may help improve the external validity of RCTS by comparing a new double–blind, placebo‐controlled randomized trial conducted in Germany with data from the US COMBINE Study.

TL;DR: The goal of the current analysis was to test this precision medicine hypothesis of the PREDICT study via analyses of subgroups, and indicated that four phenotypes could be derived using the Inventory of Drinking Situations, a 30-item self-report questionnaire.

TL;DR: In this article, the authors examined the interaction between medication and functional magnetic resonance imaging (fMRI) cue reactivity, as measured by the percentage of voxels activated, using the time to the first severe relapse as the outcome criterion, and observed an interaction effect between pretreatment brain activation induced by alcohol images and medication (acamprosate/naltrexone) on relapse behavior.

TL;DR: The findings provide a first indication that addicted Internet use is related to ADHD-like symptoms, and indicate that cluster B personality disorders and premorbid problems in emotional intelligence might present a link between problematic and addictive Internet use.

TL;DR: DCS was shown to augment the effect of CET for alcohol-dependent subjects, and the interaction between craving and ventral-striatal CR on treatment outcome suggests that CET might be especially effective in patients exhibiting both high craving and elevated CR.