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Sabrina Büttner

Researcher at Stockholm University

Publications -  89
Citations -  10518

Sabrina Büttner is an academic researcher from Stockholm University. The author has contributed to research in topics: Mitochondrion & Programmed cell death. The author has an hindex of 37, co-authored 84 publications receiving 8429 citations. Previous affiliations of Sabrina Büttner include University of Graz & University of Tübingen.

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Induction of autophagy by spermidine promotes longevity

Tobias Eisenberg, +32 more
- 01 Nov 2009 - 
TL;DR: This article showed that spermidine, a natural polyamine whose intracellular concentration declines during human ageing, markedly extended the lifespan of yeast, flies and worms, and human immune cells.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

Induction of autophagy by spermidine promotes longevity

Tobias Eisenberg, +32 more
TL;DR: Administration of spermidine markedly extended the lifespan of yeast, flies and worms, and human immune cells and inhibited oxidative stress in ageing mice, and found that enhanced autophagy is crucial for polyamine-induced suppression of necrosis and enhanced longevity.
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Cardioprotection and lifespan extension by the natural polyamine spermidine

Tobias Eisenberg, +69 more
- 01 Dec 2016 - 
TL;DR: It is shown that oral supplementation of the natural polyamine spermidine extends the lifespan of mice and exerts cardioprotective effects, reducing cardiac hypertrophy and preserving diastolic function in old mice, and suggests a new and feasible strategy for protection against cardiovascular disease.
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ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1

Guenter Haemmerle, +34 more
- 01 Sep 2011 - 
TL;DR: Reconstituting normal PPAR target gene expression by pharmacological treatment of Atgl-deficient mice with PPAR-α agonists completely reverses the mitochondrial defects, restores normal heart function and prevents premature death.