S
Sabrina Pricl
Researcher at University of Trieste
Publications - 330
Citations - 10272
Sabrina Pricl is an academic researcher from University of Trieste. The author has contributed to research in topics: Dendrimer & Multiscale modeling. The author has an hindex of 51, co-authored 318 publications receiving 9168 citations. Previous affiliations of Sabrina Pricl include Academy of Sciences of the Czech Republic & Information Technology University.
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Rheology of Industrial Polysaccharides : Theory and Applications
Romano Lapasin,Sabrina Pricl +1 more
TL;DR: The Polysaccharides: Sources And Structures as mentioned in this paper, and Industrial Applications of Polysacchides. Rheology of polysaccharide systems and their applications in industrial applications.
Journal ArticleDOI
Anticancer drug nanomicelles formed by self-assembling amphiphilic dendrimer to combat cancer drug resistance
Tuo Wei,Chao Chen,Juan Liu,Cheng Liu,Paola Posocco,Xiaoxuan Liu,Qiang Cheng,Shuaidong Huo,Zicai Liang,Maurizio Fermeglia,Sabrina Pricl,Xing-Jie Liang,Palma Rocchi,Ling Peng +13 more
TL;DR: An innovative drug delivery system based on a self-assembling amphiphilic dendrimer, which can generate supramolecular nanomicelles with large void space in their core to encapsulate anticancer drugs with high loading capacity, was established.
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Adaptive amphiphilic dendrimer-based nanoassemblies as robust and versatile siRNA delivery systems.
Xiaoxuan Liu,Jiehua Zhou,Tianzhu Yu,Chao Chen,Qiang Cheng,Kheya Sengupta,Yuanyu Huang,Haitang Li,Cheng Liu,Cheng Liu,Yang Wang,Paola Posocco,Menghua Wang,Menghua Wang,Qi Cui,Suzanne Giorgio,Maurizio Fermeglia,Fanqi Qu,Sabrina Pricl,Yanhong Shi,Zicai Liang,Palma Rocchi,John J. Rossi,Ling Peng +23 more
TL;DR: It is reported for the first time that an amphiphilic dendrimer is able to self-assemble into adaptive supramolecular assemblies upon interaction with siRNA, and effectively delivers siRNAs to various cell lines, including human primary and stem cells, thereby outperforming the currently available nonviral vectors.
Journal ArticleDOI
Activity of dasatinib against L576P KIT mutant melanoma: Molecular, cellular, and clinical correlates
Scott E. Woodman,Jonathan C. Trent,Katherine Stemke-Hale,Alexander J. Lazar,Sabrina Pricl,Giovanni M. Pavan,Maurizio Fermeglia,Y.N. Vashisht Gopal,Dan Yang,Donald A. Podoloff,Doina Ivan,Kevin B. Kim,Nicholas E. Papadopoulos,P. Hwu,Gordon B. Mills,Michael A. Davies,Michael A. Davies +16 more
TL;DR: In vitro testing showed that the cell viability of the L576P mutant cell line was not reduced by imatinib, nilotinib, or sorafenib small molecule KIT inhibitors effective in nonmelanoma cells with other KIT mutations, and thus has therapeutic implications for acrallentiginous, chronic sun-damaged, and mucosal melanomas.
Journal ArticleDOI
Degradable self-assembling dendrons for gene delivery: experimental and theoretical insights into the barriers to cellular uptake.
Anna Barnard,Paola Posocco,Sabrina Pricl,Marcelo Calderón,Rainer Haag,Mark E. Hwang,Victor W. T. Shum,Daniel W. Pack,David K. Smith +8 more
TL;DR: It is shown, both experimentally and theoretically, that gene delivery can be correlated with the ability of the dendron assemblies to release DNA, and it is shown that taking this kind of multidisciplinary approach can yield a fundamental insight into the way in which dendrons can navigate barriers to cellular uptake.