Sabrina Rizzo

TL;DR: In this article, the authors investigated the role of pathogen-associated molecular patterns (PAMPs)-pattern recognition receptors (PRRs) interaction and showed that both TLR3 and TLR7 are involved in the control of innate immunity during lung SARS-CoV-2 infection.

TL;DR: It is shown for the first time that NK cells are affected by SP1 expression in lung epithelial cells via HLA-E/NKG2A interaction and the resulting NK cells’ exhaustion might contribute to immunopathogenesis in SARS-CoV-2 infection.

TL;DR: In this article, the authors evaluated blood sHLA-E and HLA-G levels in hospitalized COVID-19 patients with respiratory failure and their relationship with clinical evolution, changes in endothelial activation biomarker profile, and neutrophil adhesion.

TL;DR: In all assays, BTRX-246040 behaves as a pure and selective antagonist at human recombinant and murine native NOP receptors displaying 3–10-fold higher potency than the standard antagonist SB-612111.

TL;DR: In this article, two transparent polymeric compounds, containing silver and benzalkonium ions electrostatically bound to a polystyrene sulfonate backbone, were synthesized, through simple procedures, and evaluated for their antimicrobial properties against Gram-positive and Gram-negative bacteria and Candida albicans, and for their antiviral activity toward 229E and SARS-CoV-2 coronavirus.