S
Sagrario Mochales
Researcher at Merck & Co.
Publications - 16
Citations - 1678
Sagrario Mochales is an academic researcher from Merck & Co.. The author has contributed to research in topics: Genus & Molecular phylogenetics. The author has an hindex of 11, co-authored 16 publications receiving 1607 citations.
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Journal ArticleDOI
Phosphonomycin, a New Antibiotic Produced by Strains of Streptomyces
David Hendlin,Edward O. Stapley,M. Jackson,Hyman Wallick,Miller Ak,Frank J. Wolf,Thomas W. Miller,Louis Chaiet,Frederick M. Kahan,Eldon L. Foltz,H. B. Woodruff,J.M. Mata,Sebastian Hernandez,Sagrario Mochales +13 more
TL;DR: Phosphonomycin is a newly discovered antibiotic produced by streptomycetes that is effective, when administered by the oral route, to mice infected with Gram-positive or Gram-negative microorganisms.
Journal ArticleDOI
Thienamycin, a new beta-lactam antibiotic. I. Discovery, taxonomy, isolation and physical properties.
Jean S. Kahan,Frederick M. Kahan,Robert T. Goegelman,Sara A. Currie,M. Jackson,Edward O. Stapley,Thomas W. Miller,Miller Ak,David Hendlin,Sagrario Mochales,Sebastian Hernandez,H. B. Woodruff,Jerome Birnbaum +12 more
TL;DR: A new beta-lactam antibiotic, named thienamycin, was discovered in culture broths of Streptomyces MA4297, and subsequently determined to be a hitherto unrecognized species, is designated StrePTomyces cattleya (NRRL 8057).
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Cephamycins, a New Family of β-Lactam Antibiotics I. Production by Actinomycetes, Including Streptomyces lactamdurans sp. n
Edward O. Stapley,M. Jackson,Sebastian Hernandez,Sheldon B. Zimmerman,Sara A. Currie,Sagrario Mochales,Mata Justo M,H. B. Woodruff,David Hendlin +8 more
TL;DR: A number of actinomycetes isolated from soil were found to produce one or more members of a new family of antibiotics, the cephamycins, which are structurally related to cephalosporin C.
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Difficidin and oxydifficidin: novel broad spectrum antibacterial antibiotics produced by Bacillus subtilis. I: Production, taxonomy and antibacterial activity
Sheldon B. Zimmerman,Cheryl D. Schwartz,Richard L. Monaghan,Barbara A. Pelak,Barbara Weissberger,Evemarie C. Gilfillan,Sagrario Mochales,Sebastian Hernandez,Sara A. Currie,Enrique Tejera,Edward O. Stapley +10 more
TL;DR: Two novel macrocyclic polyene lactone phosphate esters were discovered in fermentation broths of each of two strains of Bacillus subtilis and each showed a broad spectrum of activity against aerobic and anaerobic bacteria.
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Phylogenetic study of Hypoxylon and related genera based on ribosomal ITS sequences
Javier Sánchez-Ballesteros,Vicente González,Oscar Salazar,Javier Acero,Maria A. Portal,M.C. Julian,Víctor J. Rubio,Gerald F. Bills,Jon D. Polishook,Gonzalo Platas,Sagrario Mochales,Fernando Pelaez +11 more
TL;DR: Hypoxylon, with at least 130 currently accepted species and varieties, is one of the largest genera of the Xylariaceae as discussed by the authors, and taxonomic aspects that define and delimit the genus have varied among the authors.