Sahar El-Mekkawy

TL;DR: A new highly oxygenated triterpene named ganoderic acid alpha has been isolated from a methanol extract of the fruiting bodies of Ganoderma lucidum together with twelve known compounds by spectroscopic means including 2D-NMR.

TL;DR: The stereochemistry of 1 was established in this paper by nuclear magnetic resonance spectroscopy and was non-competitive with respect to the substrate but competitive withrespect to a template-primer.

TL;DR: Five phorbol diesters, together with three known ones, were isolated from a MeOH extract of the seeds of Croton tiglium, and their structures were determined by spectroscopic methods and selective hydrolysis of acyl groups to inhibit an HIV-induced cytopathic effect on MT-4 cells and to activate protein kinase C associated with tumor-promoting action.

TL;DR: Five pregnane glycosides were isolated from Caralluma tuberculata in addition to a known one (russelioside E, 6) and all the isolated compounds were tested for their antimalarial and antitrypanosomal activities as well as their cytotoxicity against human diploid embryonic cell line (MRC5).

TL;DR: The antiplasmodial and antitrypanosomal activity of the methanol extracts of 42 plants collected from the Kingdom of Saudi Arabia and some fractions obtained thereof were evaluated and the cytotoxicity of the active extracts was also evaluated against the MRC5 human cell line.