S
Sahar Safaei
Researcher at Tabriz University of Medical Sciences
Publications - 26
Citations - 402
Sahar Safaei is an academic researcher from Tabriz University of Medical Sciences. The author has contributed to research in topics: Cancer & microRNA. The author has an hindex of 7, co-authored 22 publications receiving 153 citations.
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Journal ArticleDOI
Current approaches for combination therapy of cancer: The role of immunogenic cell death
Zahra Asadzadeh,Elham Safarzadeh,Sahar Safaei,Ali Baradaran,Ali Mohammadi,Khalil Hajiasgharzadeh,Afshin Derakhshani,Antonella Argentiero,Nicola Silvestris,Behzad Baradaran +9 more
TL;DR: The well-characterized DAMPs are reviewed and focus on the different types of ICD inducers and recent combination therapies that can augment the immunogenicity of cancer cells.
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Combination of Ipilimumab and Nivolumab in Cancers: From Clinical Practice to Ongoing Clinical Trials.
Omid Kooshkaki,Afshin Derakhshani,Negar Hosseinkhani,Mitra Torabi,Sahar Safaei,Oronzo Brunetti,Vito Racanelli,Nicola Silvestris,Behzad Baradaran +8 more
TL;DR: Data concerning the clinical activity and the adverse events of ipilimumab and nivolumab combination therapy is reviewed, assessing ongoing clinical trials to identify clinical outlines that may support combination therapy as an effective treatment.
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Targeting ROCK signaling in health, malignant and non-malignant diseases
Roya Shahbazi,Behzad Baradaran,Monireh Khordadmehr,Sahar Safaei,Amir Baghbanzadeh,Farinaz Jigari,Hamed Ezzati +6 more
TL;DR: This review focuses on the physiological and pathological functions of ROCKs with a particular view on its possible value of ROCK inhibitors as a new therapy in cancers and non-cancer diseases.
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A comprehensive review on miR‐451: A promising cancer biomarker with therapeutic potential
Monireh Khordadmehr,Farinaz Jigari-Asl,Hamed Ezzati,Roya Shahbazi,Sanam Sadreddini,Sahar Safaei,Behzad Baradaran +6 more
TL;DR: This review will provide the critical functions of miR‐451 on biological mechanisms including cell cycle and proliferation, cell survival and apoptosis, differentiation and development as well as disease initiation and progression such as tumor formation, migration, invasion, and metastasis.
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A Systematic Review on the Therapeutic Potentiality of PD-L1-Inhibiting MicroRNAs for Triple-Negative Breast Cancer: Toward Single-Cell Sequencing-Guided Biomimetic Delivery.
Mahdi Abdoli Shadbad,Sahar Safaei,Oronzo Brunetti,Afshin Derakhshani,Parisa Lotfinejad,Ahad Mokhtarzadeh,Nima Hemmat,Vito Racanelli,Antonio Giovanni Solimando,Antonella Argentiero,Nicola Silvestris,Behzad Baradaran +11 more
TL;DR: In this paper, the authors conducted a systematic review based on the preferred reporting items for systematic reviews and meta-analyses (PRISMA) to provide a comprehensive and unbiased synthesis of currently available evidence regarding the effect of PD-L1-inhibiting miRs restoration on TNBC development and tumor microenvironment.