S
Sai Priya Anand
Researcher at McGill University
Publications - 46
Citations - 1802
Sai Priya Anand is an academic researcher from McGill University. The author has contributed to research in topics: Antibody & Antibody-dependent cell-mediated cytotoxicity. The author has an hindex of 15, co-authored 37 publications receiving 809 citations. Previous affiliations of Sai Priya Anand include Université de Montréal & University of Ottawa.
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Journal ArticleDOI
Cross-Sectional Evaluation of Humoral Responses against SARS-CoV-2 Spike.
Jérémie Prévost,Romain Gasser,Guillaume Beaudoin-Bussières,Jonathan Richard,Ralf Duerr,Annemarie Laumaea,Sai Priya Anand,Guillaume Goyette,Mehdi Benlarbi,Shilei Ding,Halima Medjahed,Antoine Lewin,Josée Perreault,Tony Tremblay,Gabrielle Gendron-Lepage,Nicolas Gauthier,Marc Carrier,Diane Marcoux,Alain Piché,Myriam Lavoie,Alexandre Benoit,Vilayvong Loungnarath,Gino Brochu,Elie Haddad,Hannah D. Stacey,Matthew S. Miller,Marc Desforges,Pierre J. Talbot,Graham T. Gould Maule,Marceline Côté,Christian Therrien,Bouchra Serhir,Renée Bazin,Michel Roger,Andrés Finzi,Andrés Finzi +35 more
TL;DR: While most of individuals develop neutralizing antibodies within two weeks of infection, the level ofneutralizing activity is significantly decreased over time, highlighting the importance of studying the persistence of neutralizing activity upon natural SARS-CoV-2 infection.
Journal ArticleDOI
Decline of Humoral Responses against SARS-CoV-2 Spike in Convalescent Individuals.
Guillaume Beaudoin-Bussières,Annemarie Laumaea,Sai Priya Anand,Jérémie Prévost,Romain Gasser,Guillaume Goyette,Halima Medjahed,Josée Perreault,Tony Tremblay,Antoine Lewin,Laurie Gokool,Chantal Morrisseau,Philippe Bégin,Cécile Tremblay,Valérie Martel-Laferrière,Daniel Kaufmann,Jonathan Richard,Renée Bazin,Andrés Finzi,Andrés Finzi +19 more
TL;DR: How the humoral responses against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Spike glycoprotein, including neutralization, evolve over time is evaluated to suggest that plasma from convalescent donors should be recovered rapidly after resolution of symptoms.
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A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses.
Alexandra Tauzin,Manon Nayrac,Mehdi Benlarbi,Shang Yu Gong,Romain Gasser,Guillaume Beaudoin-Bussières,Nathalie Brassard,Annemarie Laumaea,Dani Vézina,Jérémie Prévost,Sai Priya Anand,Catherine Bourassa,Gabrielle Gendron-Lepage,Halima Medjahed,Guillaume Goyette,Julia Niessl,Olivier Tastet,Laurie Gokool,Chantal Morrisseau,Pascale Arlotto,Leonidas Stamatatos,Leonidas Stamatatos,Andrew T. McGuire,Catherine Larochelle,Pradeep D. Uchil,Maolin Lu,Walther Mothes,Gaston De Serres,Sandrine Moreira,Michel Roger,Jonathan Richard,Valérie Martel-Laferrière,Ralf Duerr,Cécile Tremblay,Daniel Kaufmann,Andrés Finzi,Andrés Finzi +36 more
TL;DR: In this article, a single dose of the BNT162b2 mRNA vaccine for SARS-CoV-2 was found to be up to 90% effective starting 14 days post-administration.
Journal ArticleDOI
Real-Time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles.
Maolin Lu,Pradeep D. Uchil,Wenwei Li,Desheng Zheng,Daniel S. Terry,Jason Gorman,Wei Shi,Baoshan Zhang,Tongqing Zhou,Shilei Ding,Romain Gasser,Jérémie Prévost,Guillaume Beaudoin-Bussières,Sai Priya Anand,Sai Priya Anand,Annemarie Laumaea,Jonathan R. Grover,Lihong Liu,David D. Ho,John R. Mascola,Andrés Finzi,Andrés Finzi,Peter D. Kwong,Scott C. Blanchard,Walther Mothes +24 more
TL;DR: Conformational preferences observed upon expsoure to convalescent plasma or antibodies suggest mechanisms of neutralization involving either competition with hACE2 for binding to the receptor-binding domain (RBD) or allosteric interference with conformational changes required for entry.
Journal ArticleDOI
Longitudinal analysis of humoral immunity against SARS-CoV-2 Spike in convalescent individuals up to 8 months post-symptom onset.
Sai Priya Anand,Jérémie Prévost,Manon Nayrac,Guillaume Beaudoin-Bussières,Mehdi Benlarbi,Romain Gasser,Nathalie Brassard,Annemarie Laumaea,Shang Yu Gong,Catherine Bourassa,Elsa Brunet-Ratnasingham,Halima Medjahed,Gabrielle Gendron-Lepage,Guillaume Goyette,Laurie Gokool,Chantal Morrisseau,Philippe Bégin,Valérie Martel-Laferrière,Cécile Tremblay,Jonathan Richard,Renée Bazin,Ralf Duerr,Daniel Kaufmann,Andrés Finzi,Andrés Finzi +24 more
TL;DR: In this article, the presence of SARS-CoV-2-specific memory B cells in convalescent individuals was evaluated using a longitudinal assessment of humoral immune responses.