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Sajad Khosravi

Bio: Sajad Khosravi is an academic researcher. The author has an hindex of 1, co-authored 1 publications receiving 1 citations.

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TL;DR: In this paper, pine pollen extracts were used to synthesize green-synthesized zinc oxide nanoparticles (K-doped ZnO NPs), which were analyzed using X-ray diffraction (XRD), inductively coupled plasma atomic emission spectroscopy (ICP-AES), scanning electron microscopy (SEM), and transmission electron microscopy (TEM).
Abstract: In this study, potassium-doped zinc oxide nanoparticles (K-doped ZnO NPs) were green-synthesized using pine pollen extracts based on bioethics principles. The synthesized NPs were analyzed using X-ray diffraction (XRD), inductively coupled plasma atomic emission spectroscopy (ICP-AES), scanning electron microscopy (SEM), energy-dispersive X-ray analysis (EDXA), and transmission electron microscopy (TEM). The cytotoxicity of these nanoparticles (NPs) on normal macrophage cells and cancer cell lines was evaluated. In the same concentrations of K-doped ZnO and pure ZnO NPs, K-doped ZnO NPs demonstrated higher toxicity. The results confirmed that the doped potassium could increase cytotoxicity. The IC50 of K-doped ZnO NPs, pure ZnO NPs, and the examined control drug were 497 ± 15, 769 ± 12, and 606 ± 19 µg/mL, respectively. Considering the obtained IC50 of K-doped ZnO NPs, they were more toxic to the cancer cell lines and had less cytotoxicity on normal macrophage cells.

19 citations


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TL;DR: In this article , bimetallic CuO/ZnO nanostructures were biosynthesized using plant extracts and the plant-mediated synthesis nanoparticles were characterized by Transmission electron microscopy (TEM), X-ray diffraction analysis (XRD), Field Emission Scanning Electron Microscopy (FESEM) and Energy-Dispersive Spectroscopy (EDAX).
Abstract: Bimetallic nanoparticles offer unique chemical, physical and optical properties that are not available for monometallic nanoparticles. Bimetallic nanoparticles play a major role in various therapeutic, industrial and energy fields. Recently, nanoparticles of Copper/Zinc bimetallic nanoparticles have attracted attention in various fields, especially medicine. In this study, bimetallic CuO/ZnO nanostructures were biosynthesized using plant extracts. The plant-mediated synthesis nanoparticles were characterized by Transmission electron microscopy (TEM), X-ray diffraction analysis (XRD), Field Emission Scanning Electron Microscopy (FESEM) and Energy-Dispersive Spectroscopy (EDAX). The cytotoxicity of plant-mediated synthesis bimetallic nanoparticles and the synergistic effects of these nanoparticles in combination with the anticancer drug doxorubicin on MCF-7 cancer cells were evaluated by MTT assay.

46 citations

Journal ArticleDOI
TL;DR: In this paper , the authors discuss bioimaging, chemotherapy, phototherapy, targeted drug/gene delivery, and challenges of utilizing RMSNs as a promising strategy for cancer theranostics.

21 citations

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TL;DR: This work reviews microorganisms-based synthesis of nanoparticles containing gold, silver, platinum, palladium, copper, titanium dioxide, zinc oxide, iron oxide, and selenium and presents nanoparticle properties and applications in waste treatment, cancer treatment, antibacterial, antimicrobial, antifungal, and antioxidants.

18 citations

Journal ArticleDOI
TL;DR: In this paper , magnetic spinel copper ferrite (CuFe2O4) nanostructures were eco-friendly synthesized using Nasturtium officinale extract, and their physicochemical properties were determined by transmission electron microscopy, FEM, X-ray diffraction, and vibrating sample magnetometry.
Abstract: Abstract In this study, magnetic spinel copper ferrite (CuFe2O4) nanostructures were eco-friendly synthesized using Nasturtium officinale extract. Physicochemical properties of these nanostructures were determined by transmission electron microscopy, field emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD), vibrating sample magnetometry, and energy dispersive X-ray mapping analysis. XRD patterns conform to the CuFe2O4 formation. SEM results demonstrated ceramic spinel CuFe2O4 nanostructures with spherical surface morphologies. The cytotoxicity effect of CuFe2O4 nanostructures against rat pheochromocytoma (PC12) cells was evaluated based on MTT assay. The magnetic nanostructures had low toxicity at a concentration of 250 µg/mL. It appears that these nanostructures can be considered as suitable candidates for drug delivery and other biomedical applications, because of their low toxicity effects.

18 citations

Journal ArticleDOI
TL;DR: In this paper , a mixture of two phenolic extracts of rosemary and Echinacea was utilized as stabilizing and reducing agents for the synthesis of Goethite (FeOOH) nanoparticles without utilizing harmful toxic solvents.
Abstract: Iron oxyhydroxide (α-FeOOH, Goethite) is one of the most thermodynamically stable iron oxides and a widespread soil mineral. In this study, a mixture of two phenolic extracts of rosemary and Echinacea was utilized as stabilizing and reducing agents for the synthesis of Goethite (FeOOH) nanoparticles without utilizing harmful toxic solvents. The resulting nanoparticles were characterized by X-ray powder diffraction (XRD), field emission scanning electron microscopy (FESEM)-energy dispersive spectroscopy (EDS), transmission electron microscopy (TEM), vibrating-sample magnetometer (VSM), thermogravimetry/differential thermal analysis (TG/DTA), and Brunauer–Emmett-Teller (BET). MTT assay was applied for evaluating the possible toxicity of the nanoparticles against A549 human lung adenocarcinoma cells.

14 citations