S
Sami A. Khalid
Researcher at University of Khartoum
Publications - 61
Citations - 2352
Sami A. Khalid is an academic researcher from University of Khartoum. The author has contributed to research in topics: Antiprotozoal & Medicine. The author has an hindex of 25, co-authored 58 publications receiving 2198 citations. Previous affiliations of Sami A. Khalid include University of Strathclyde & Universiti Putra Malaysia.
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Journal ArticleDOI
The Potential of Secondary Metabolites from Plants as Drugs or Leads Against Protozoan Neglected Diseases – Part I
Thomas J. Schmidt,Sami A. Khalid,Alvaro J. Romanha,T. Ma. Alves,Maique W. Biavatti,Reto Brun,FB Da Costa,S. L. De Castro,Vitor F. Ferreira,M. V. G. de Lacerda,João Henrique G. Lago,Leonor L. Leon,Norberto Peporine Lopes,R. C. das Neves Amorim,Michael Niehues,Ifedayo Victor Ogungbe,Adrian Martin Pohlit,Marcus Tullius Scotti,William N. Setzer,M. de N. C. Soeiro,M. Steindel,Andre G. Tempone +21 more
TL;DR: The current review attempts to give an overview on the potential of such plant-derived natural products as antiprotozoal leads and/or drugs in the fight against NTDs.
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Isolation and characterization of an antimalarial agent of the neem tree Azadirachta indica.
TL;DR: The isolation and structure elucidation of gedunin, the antimalarial agent of Azadirachta indica, are reported using one- and two-dimensional nmr spectroscopy, especially homonuclear and heteronuclear COSY, nOe difference, and COLOC experiments.
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Potential antimalarial candidates from African plants: An in vitro approach using Plasmodium falciparum☆
TL;DR: In this protocol, the flavonoid quercetin purified from Diosma pilosa was found to have the same activity as a commercially obtained preparation, and simple radiometric assays for antimalarial activity can be used to rapidly screen purified plant material or secondary plant metabolites.
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Antiplasmodial activity of selected Sudanese medicinal plants with emphasis on Maytenus senegalensis (Lam.) Exell.
TL;DR: Most of the plants from the family Meliaceae showed highly potent antiplasmodial activity against the two tested strains and terpenoids and traces of phenolic principles but no alkaloid, tannins or flavonoids were detected.
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Antiplasmodial activity of selected sudanese medicinal plants with emphasis on Acacia nilotica.
TL;DR: Phytochemical analysis indicated that the most active phase contained terpenoids and tannins and was devoid of alkaloids and saponins, and the effect of plant extracts on lymphocyte proliferation showed low toxicity to the human cells.