Samuel B. Guze

Bio: Samuel B. Guze is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Hysteria & Poison control. The author has an hindex of 52, co-authored 157 publications receiving 17620 citations. Previous affiliations of Samuel B. Guze include University of Minnesota & University of Kansas.

Diagnostic criteria for use in psychiatric research.

Abstract: Diagnostic criteria for 14 psychiatric illnesses (and for secondary depression) along with the validating evidence for these diagnostic categories comes from workers outside our group as well as from those within; it consists of studies of both outpatients and inpatients, of family studies, and of follow-up studies. These criteria are the most efficient currently available; however, it is expected that the criteria be tested and not be considered a final, closed system. It is expected that the criteria will change as various illnesses are studied by different groups. Such criteria provide a framework for comparison of data gathered in different centers, and serve to promote communication between investigators.

Establishment of Diagnostic Validity in Psychiatric Illness: Its Application to Schizophrenia

Abstract: A method for achieving diagnostic validity in psychiatric illness is described, consisting of five phases: clinical description, laboratory study, exclusion of other disorders, follow-up study, and family study. The method was applied in this paper to patients with the diagnosis of schizophrenia, and it was shown by follow-up and family studies that poor prognosis cases can be validly separated clinically from good prognosis cases. The authors conclude that good prognosis "schizophrenia" is not mild schizophrenia, but a different illness.

Alcohol Problems in Adoptees Raised Apart From Alcoholic Biological Parents

Abstract: Drinking practices and problems, plus a wide range of other life experiences, were studied in a group of 55 men who had been separated from their biological parents early in life where one parent had a hospital diagnosis of alcoholism Compared to a matched control group of adoptees, significantly more of them had a history of drinking problems and psychiatric treatment The two groups did not differ with regard to other forms of psychopathology, such as depression or character disorders Children of alcoholics had three times the divorce rate of the controls Apart from alcohol problems and divorce, the two groups did not differ significantly with regard to any other variable studied The adoptive parents of index and control subjects were of similar socioeconomic class and had similar rates of alcoholism and other psychiatric disorders These findings suggest that genetic factors may play a role in the development of alcohol problems

Studies in hysteria.

Abstract: This paper describes how the idea of substituting “Briquet Syndrome” for “Hysteria” developed. It emphasizes the need to base the diagnosis firmly on clinical features and also the value of differentiating “polysymptomatic” forms (Briquet Syndrome) from “conversion” symptoms (unexplained neurological symptoms). Other studies have shown that there is a preponderance of Briquet's Syndrome in women, and that female relatives of patients have an increased prevalence of Briquet's Syndrome, while male relatives have an increased prevalence of antisocial personality and of alcoholism. Conversely, a study of female relatives of a male prison population reveals a high prevalence of Briquet's Syndrome amongst them.It is suggested that the association between Briquet's Syndrome and antisocial personality may explain many clinical and epidemiologic observations.

Suicide and Primary Affective Disorders

Abstract: Primary affective disorders, depressive or manic episodes in patients who have been psychiatrically well previously, or who have had episodes of mania or depression without other psychiatric illnesses (Robins and Guze, 1969), are associated with high suicide rates. The following data indicate that the suicide risk among these patients is over thirty times greater than that of the population without these disorders, and that the risk of suicide compared to other causes of death may be increased early in the course of the illness.

The Mini-International Neuropsychiatric Interview (M.I.N.I.) : The development and validation of a Structured Diagnostic Psychiatric Interview for DSM-IV and ICD-10

Abstract: The Mini-International Neuropsychiatric Interview (M.I.N.I.) is a short structured diagnostic interview, developed jointly by psychiatrists and clinicians in the United States and Europe, for DSM-IV and ICD-10 psychiatric disorders. With an administration time of approximately 15 minutes, it was designed to meet the need for a short but accurate structured psychiatric interview for multicenter clinical trials and epidemiology studies and to be used as a first step in outcome tracking in nonresearch clinical settings. The authors describe the development of the M.I.N.I. and its family of interviews: the M.I.N.I.-Screen, the M.I.N.I.-Plus, and the M.I.N.I.-Kid. They report on validation of the M.I.N.I. in relation to the Structured Clinical Interview for DSM-III-R, Patient Version, the Composite International Diagnostic Interview, and expert professional opinion, and they comment on potential applications for this interview.

A new depression scale designed to be sensitive to change.

Abstract: The construction of a depression rating scale designed to be particularly sensitive to treatment effects is described. Ratings of 54 English and 52 Swedish patients on a 65 item comprehensive psychopathology scale were used to identify the 17 most commonly occurring symptoms in primary depressive illness in the combined sample. Ratings on these 17 items for 64 patients participating in studies of four different antidepressant drugs were used to create a depression scale consisting of the 10 items which showed the largest changes with treatment and the highest correlation to overall change. The inner-rater reliability of the new depression scale was high. Scores on the scale correlated significantly with scores on a standard rating scale for depression, the Hamilton Rating Scale (HRS), indicating its validity as a general severity estimate. Its capacity to differentiate between responders and non-responders to antidepressant treatment was better than the HRS, indicating greater sensitivity to change. The practical and ethical implications in terms of smaller sample sizes in clinical trials are discussed.

The ethnographic interview

Abstract: Part I. Ethnographic Research: Ethnography and Culture. Language and Field Work. Informants. Part II. The Developmental Research Sequences: Locating an Informant. Interviewing an Informant. Making an Ethnographic Record. Asking Descriptive Questions. Analyzing Ethnographic Interviews. Making a Domain Analysis. Asking Structural Questions. Making a Taxonomic Analysis. Asking Contrast Questions. Making a Componential Analysis. Discovering Cultural Themes. Writing an Ethnography. Notes. Appendices: A Taxonomy of Ethnographic Questions. Developmental Research Sequence Writing Tasks. The Development Research Sequence Method. Bibliography. Index.

Cognitive Therapy of Depression

Abstract: 1. An Overview 2. The Role of Emotions in Cognitive Therapy 3. The Therapeutic Relationship: Application to Cognitive Therapy 4. Structure of the Therapeutic Interview 5. The Initial Interview 6. Session by Session Treatment: A Typical Course of Therapy 7. Application of Behavioral Techniques 8. Cognitive Techniques 9. Focus on Target Symptoms 10. Specific Techniques for the Suicidal Patient 11. Interview with a Depressed Suicidal Patient 12. Depressogenic Assumptions 13. Integration of Homework into Therapy 14. Technical Problems 15. Problems Related to Termination and Relapse 16. Group Cognitive Therapy for Depressed Patients Steven D. Hollon and Brian F. Shaw 17. Cognitive Therapy and Antidepressant Medications 18. Outcome Studies of Cognitive Therapy Appendix: Materials *The Beck Inventory *Scale for Suicide Ideation *Daily Record of Dysfunctional Thoughts *Competency Checklist for Cognitive Therapists *Possible Reasons for Not Doing Self-Help Assignments *Research Protocol for Outcome Study at Center for Cognitive Therapy *Further Materials and Technical Aids

Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): Initial Reliability and Validity Data

Abstract: Objective To describe the psychometric properties of the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version (K-SADS-PL) interview, which surveys additional disorders not assessed in prior K-SADS, contains improved probes and anchor points, includes diagnosis-specific impairment ratings, generates DSM-III-R and DSM-IV diagnoses, and divides symptoms surveyed into a screening interview and five diagnostic supplements. Method Subjects were 55 psychiatric outpatients and 11 normal controls (aged 7 through 17 years). Both parents and children were used as informants. Concurrent validity of the screen criteria and the K-SADS-PL diagnoses was assessed against standard self-report scales. Interrater ( n = 15) and test-retest ( n = 20) reliability data were also collected (mean retest interval: 18 days; range: 2 to 38 days). Results Rating scale data support the concurrent validity of screens and K-SADS-PL diagnoses. Interrater agreement in scoring screens and diagnoses was high (range: 93% to 100%). Test-retest reliability κ coefficients were in the excellent range for present and/or lifetime diagnoses of major depression, any bipolar, generalized anxiety, conduct, and oppositional defiant disorder (.77 to 1.00) and in the good range for present diagnoses of posttraumatic stress disorder and attention-deficit hyperactivity disorder (.63 to .67). Conclusion Results suggest the K-SADS-PL generates reliable and valid child psychiatric diagnoses. J. Am. Acad. Child Adolesc. Psychiatry , 1997, 36(7): 980–988.