Samuel Klein

TL;DR: It is shown that the relative proportion of Bacteroidetes is decreased in obese people by comparison with lean people, and that this proportion increases with weight loss on two types of low-calorie diet.

TL;DR: Although both IL-6 and TNF alpha are expressed by adipose tissue, the results show that there are important differences in their systemic release.

TL;DR: The low-carbohydrate diet produced a greater weight loss than did the conventional diet for the first six months, but the differences were not significant at one year and the low- carbohydrate diet was associated with a greater improvement in some risk factors for coronary heart disease.

TL;DR: It is not clear whether NAFLD causes metabolic dysfunction or whether metabolic dysfunction is responsible for IHTG accumulation, or possibly both, but it is likely that abnormalities in fatty acid metabolism are key factors involved in the development of insulin resistance, dyslipidemia, and other cardiometabolic risk factors associated withNAFLD.

TL;DR: The data suggest that visceral fat is an important site for IL-6 secretion and provide a potential mechanistic link between visceral fat and systemic inflammation in people with abdominal obesity.