Sandhya Mishra

Bio: Sandhya Mishra is an academic researcher from South China Agricultural University. The author has contributed to research in topics: Bioremediation & Hexavalent chromium. The author has an hindex of 14, co-authored 30 publications receiving 866 citations. Previous affiliations of Sandhya Mishra include Babasaheb Bhimrao Ambedkar University.

Toxic and genotoxic effects of hexavalent chromium in environment and its bioremediation strategies

Abstract: Chromium is one of the major inorganic environmental pollutants, which is added in the environment through various natural and anthropogenic activities and exists mainly in two forms: Cr(III) and Cr(VI). Cr(VI) is considered to be more toxic than Cr(III) due to its high solubility and mobility. It is a well-reported occupational carcinogen associated with lung, nasal, and sinus cancers. Thus, this review article provides the detailed information on the occurrence, sources of chromium contamination in the environment and their toxicological effects in human, animal, plants as well as in microorganisms, and bioremediation strategies to minimize the toxic effects.

Heavy Metal Contamination: An Alarming Threat to Environment and Human Health

Abstract: Metals naturally exist in the crust of the earth, and their compositions vary among different localities, resulting in structural disparity of surrounding concentrations. Some heavy metals are much important in trace amounts in respect to living organisms related to their metabolic activities. High solubility of various heavy metals changes them into extremely toxic and perilous contaminant of water and soil when discharged by many industrial activities. When these metals are released into the environment, they can be leached into the underground waters, depositing in the aquifers, or run off into surface waters and soils thereby resulting in water and soil pollution. Thus, heavy metals become a potential contaminant for environment that can partake in trophic transfer in food chains. The toxicity of heavy metals mainly depends upon its relative oxidation state, which is responsible for physiological bio-toxic effects. When these metals enter into the living organisms, they, combine with proteins, enzymes, and DNA molecules, form highly stable bio-toxic compounds, thus altering their proper functioning and obstructing them from the bioreactions. Arsenic, chromium, cadmium, and lead are highly toxic and produce mutagenic, carcinogenic, and genotoxic effects. Hence, this chapter is focused on occurrence and allocation of heavy metals, their toxicological impact on environment, and their possible eco-friendly remedies for green and healthy environment.

Kirk-Othmer Encyclopedia of Chemical Technology数据库介绍及实例

Abstract: 介绍了Kirk—Othmer Encyclopedia of Chemical Technology（化工技术百科全书）（第五版）电子图书网络版数据库，并对该数据库使用方法和检索途径作出了说明，且结合实例简单地介绍了该数据库的检索方法。

Toxicity and Bioremediation of Heavy Metals Contaminated Ecosystem from Tannery Wastewater: A Review

Abstract: The discharge of untreated tannery wastewater containing biotoxic substances of heavy metals in the ecosystem is one of the most important environmental and health challenges in our society. Hence, there is a growing need for the development of novel, efficient, eco-friendly, and cost-effective approach for the remediation of inorganic metals (Cr, Hg, Cd, and Pb) released into the environment and to safeguard the ecosystem. In this regard, recent advances in microbes-base heavy metal have propelled bioremediation as a prospective alternative to conventional techniques. Heavy metals are nonbiodegradable and could be toxic to microbes. Several microorganisms have evolved to develop detoxification mechanisms to counter the toxic effects of these inorganic metals. This present review offers a critical evaluation of bioremediation capacity of microorganisms, especially in the context of environmental protection. Furthermore, this article discussed the biosorption capacity with respect to the use of bacteria, fungi, biofilm, algae, genetically engineered microbes, and immobilized microbial cell for the removal of heavy metals. The use of biofilm has showed synergetic effects with many fold increase in the removal of heavy metals as sustainable environmental technology in the near future.

A critical review on bioremediation technologies for Cr(VI)-contaminated soils and wastewater

Abstract: Chromium (Cr) is a potentially toxic metal originating from natural processes and anthropogenic activities such as the iron-steel, electroplating, and leather industries, which is carcinogen to liv...

Heavy Metal Contamination: An Alarming Threat to Environment and Human Health

Abstract: Metals naturally exist in the crust of the earth, and their compositions vary among different localities, resulting in structural disparity of surrounding concentrations. Some heavy metals are much important in trace amounts in respect to living organisms related to their metabolic activities. High solubility of various heavy metals changes them into extremely toxic and perilous contaminant of water and soil when discharged by many industrial activities. When these metals are released into the environment, they can be leached into the underground waters, depositing in the aquifers, or run off into surface waters and soils thereby resulting in water and soil pollution. Thus, heavy metals become a potential contaminant for environment that can partake in trophic transfer in food chains. The toxicity of heavy metals mainly depends upon its relative oxidation state, which is responsible for physiological bio-toxic effects. When these metals enter into the living organisms, they, combine with proteins, enzymes, and DNA molecules, form highly stable bio-toxic compounds, thus altering their proper functioning and obstructing them from the bioreactions. Arsenic, chromium, cadmium, and lead are highly toxic and produce mutagenic, carcinogenic, and genotoxic effects. Hence, this chapter is focused on occurrence and allocation of heavy metals, their toxicological impact on environment, and their possible eco-friendly remedies for green and healthy environment.