S
Sandra Orozco-Suárez
Researcher at Mexican Social Security Institute
Publications - 106
Citations - 1203
Sandra Orozco-Suárez is an academic researcher from Mexican Social Security Institute. The author has contributed to research in topics: Epilepsy & Status epilepticus. The author has an hindex of 17, co-authored 97 publications receiving 884 citations. Previous affiliations of Sandra Orozco-Suárez include National Autonomous University of Mexico.
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Journal ArticleDOI
Antioxidant, antiinflammatory and antiapoptotic effects of dapsone in a model of brain ischemia/reperfusion in rats.
Araceli Diaz-Ruiz,Carlos Zavala,Sergio Montes,Alma Ortiz-Plata,Hermelinda Salgado-Ceballos,Sandra Orozco-Suárez,Concepción Nava-Ruiz,Iván Pérez-Neri,Francisca Pérez-Severiano,Camilo Ríos +9 more
TL;DR: Dapsone antagonized all of the I/R end points measured, showing a remarkable ability to decrease markers of damage through antioxidant, antiinflammatory, and anti‐apoptotic effects.
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Effects of high frequency electrical stimulation and R-verapamil on seizure susceptibility and glutamate and GABA release in a model of phenytoin-resistant seizures.
TL;DR: It is concluded that alterations of glutamate and GABA release in the epileptic hippocampus of non-responsive animals resemble those found in hippocampus of patients with refractory TLE.
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Anticonvulsive effect of vitamin C on pentylenetetrazol-induced seizures in immature rats ☆
Misael González-Ramírez,León I. Razo-Juárez,José L. Sauer-Ramírez,Ma. Eva González-Trujano,Hermelinda Salgado-Ceballos,Sandra Orozco-Suárez +5 more
TL;DR: The results suggest that vitamin C together with progesterone and/or its metabolites are involved in the protection against PTZ-induced seizures in immature rats.
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Influence of genetic variants of CYP2D6, CYP2C9, CYP2C19 and CYP3A4 on antiepileptic drug metabolism in pediatric patients with refractory epilepsy.
Miguel A. López-García,Iris A. Feria-Romero,Héctor Serrano,Darío Rayo-Mares,Pietro Fagiolino,Marta Vázquez,Consuelo Escamilla-Núñez,Israel Grijalva,David Escalante-Santiago,Sandra Orozco-Suárez +9 more
TL;DR: The results demonstrated the important role of the CYP 3A4*1B allelic variant as risk factor for developing drug resistance and CYP 2D6, CYP2C19 SNPs and haplotypes may affect the response to antiepileptic drugs.
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GABAergic alterations in neocortex of patients with pharmacoresistant temporal lobe epilepsy can explain the comorbidity of anxiety and depression: the potential impact of clinical factors.
Luisa Rocha,Mario Alonso-Vanegas,Iris E. Martínez-Juárez,Sandra Orozco-Suárez,David Escalante-Santiago,Iris A. Feria-Romero,Cecilia Zavala-Tecuapetla,José Miguel Cisneros-Franco,Ricardo Masao Buentello-García,Jesús Cienfuegos +9 more
TL;DR: A dysfunction of the GABAergic neurotransmission in temporal neocortex of patients with TLE and comorbid anxiety and/or depression that could be also influenced by clinical factors such as seizure frequency and duration of illness is suggested.