S
Sandrine Alibert
Researcher at Aix-Marseille University
Publications - 17
Citations - 385
Sandrine Alibert is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Efflux & Enterobacter aerogenes. The author has an hindex of 11, co-authored 17 publications receiving 350 citations. Previous affiliations of Sandrine Alibert include Institute of Tropical Medicine Antwerp & Centre national de la recherche scientifique.
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Journal ArticleDOI
Chloroquine Resistance Reversal Agents as Promising Antimalarial Drugs
Maud Henry,Sandrine Alibert,Eve Orlandi-Pradines,Hervé Bogreau,Thierry Fusai,Christophe Rogier,Jacques Barbe,Bruno Pradines +7 more
TL;DR: Progress made in biochemical and genetic basis of antimalarial resistance is summarized, emphasizing the recent developments on drugs, which interfere with trans membrane proteins involved in drug efflux or uptake.
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Synthesis and effects on chloroquine susceptibility in Plasmodium falciparum of a series of new dihydroanthracene derivatives.
Sandrine Alibert,Christiane Santelli-Rouvier,Bruno Pradines,Carole Houdoin,Daniel Parzy,Janina Karolak-Wojciechowska,Jacques Barbe +6 more
TL;DR: To suggest a mechanism of action for drugs capable to reverse the chloroquine resistance, a new set of 9, 10-dihydro-9,10-ethano and ethenoanthracene derivatives was synthesized and compounds were tested to propose a putative model of interaction with some selected amino acids.
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Amine-alkyl derivatives of hydantoin: new tool to combat resistant bacteria.
Jadwiga Handzlik,Ewa Szymańska,Jacqueline Chevalier,Ewa Otrębska,Katarzyna Kieć-Kononowicz,Jean-Marie Pagès,Sandrine Alibert +6 more
TL;DR: According to SAR-studies, hit compounds containing 2-methoxyphenylpiperazine at N1-terminal fragment and methylcarboxyl acid one at N3-position of hydantoin have been identified for further microbiological studies and pharmacomodulations to develop efflux pump inhibitors.
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Inhibition of efflux of quinolines as new therapeutic strategy in malaria.
TL;DR: The main elements of quinoline resistance and reversion of qu inoline resistance related to malaria are summarized.
Journal ArticleDOI
Multidrug efflux pumps and their role in antibiotic and antiseptic resistance: a pharmacodynamic perspective
Sandrine Alibert,Joannah N 'Gompaza Diarra,Jessica Hernandez,Aurélien Stutzmann,Marwa A. Fouad,Gérard Boyer,Jean-Marie Pagès +6 more
TL;DR: Efflux pumps are new targets for the development of adjuvant in antibiotic treatments by of efflux pump inhibition and may allow us to rejuvenate old antibiotics acting on their concentration inside the bacteria and thus potentiating their activity while blocking the release of virulence factors.