Sang-Hyo Kim

Bio: Sang-Hyo Kim is an academic researcher from Sungkyunkwan University. The author has contributed to research in topics: Low-density parity-check code & Decoding methods. The author has an hindex of 23, co-authored 211 publications receiving 2049 citations. Previous affiliations of Sang-Hyo Kim include Seoul National University & Qualcomm.

Electrical cell-substrate impedance sensing as a non-invasive tool for cancer cell study

Abstract: Cell-substrate interactions are investigated in a number of studies for drug targets including angiogenesis, arteriosclerosis, chronic inflammatory diseases and carcinogenesis. One characteristic of malignant cancerous cells is their ability to invade tissue. Cell adhesion and cytoskeletal activity have served as valuable indicators for understanding the cancer cell behaviours, such as proliferation, migration and invasion. This review focuses on bio-impedance based measurement for monitoring the behaviours in real time and without using labels. Electric cell-substrate impedance sensing (ECIS) provides rich information about cell-substrate interactions, cell-cell communication and cell adhesion. High sensitivity of the ECIS method allows for observing events down to single-cell level and achieving nanoscale resolution of cell-substrate distances. Recently, its miniaturization and integration with fluorescent detection techniques have been highlighted as a new tool to deliver a high-content platform for anticancer drug development.

Polymer Nanoparticles for Smart Drug Delivery

Abstract: In the recent decades, polymers are widely used as biomaterials due to their favorable properties such as good biocompatibility, easy design and preparation, a variety of structures and interesting bio-mimetic character. Especially in the field of smart drug delivery, polymer played a significant role because it can deliver therapeutic agents directly into the intended site of action, with superior efficacy. The ideal requirements for designing nano-particulate delivery system are to effectively be controlled particle size, surface character; enhance permeation, flexibility, solubility and release of therapeutically active agents in order to attain the target and specific activity at a predetermined rate and time. The smart drug delivery systems have been successfully made by the advances in polymer science in the bio-nano‐ technology field. Recently, these advances have been found in various medical applications for nano-scale structures in smart drug delivery. The smart drug delivery systems should possess some important feature such as pre-scheduled rate, self controlled, targeted, predetermined time and monitor the delivery. The smart drug delivery system enhances the polymer nanoparticle better stage to their therapy regimen. They are drug carriers of natural, semi-synthetic, and synthetic polymeric nature at the nano-scale to micro-scale range. The polymeric particles are collectively named as spheres and capsules. The most of the polymeric nanoparticles with surfactants offer stability of various forms of active drugs and have useful to smart release properties. There are numerous biological applications have been reported for the nano-scale to micro-scale sized particles, such as site-targeted, controlled, and enhanced bioavailability of hydrophobic drugs [1-4]. Due to the nanoparticles size the drugs have been targeting into various applications, such as, various cancers targeting has been shown to be promising [5]. Moreover, polymeric particles proved their effectiveness in stabilizing and protecting the drug molecules such as proteins, peptides, or DNA molecules from various environmental hazards degradation [2-4, 6, 7]. So these polymers are affording the potential for various protein and gene delivery. Numerous methods had been available to fabricate

AC frequency characteristics of coplanar impedance sensors as design parameters.

Abstract: Glass-based microchannel chips were fabricated using photolithographic technology, and Pt thin-film microelectrodes, as coplanar impedance sensors, were integrated on them. Longitudinal design parameters, such as interelectrode spacing and electrode width, of coplanar impedance sensors were changed to determine AC frequency characteristics as design parameters. Through developing total impedance equations and modeling equivalent circuits, the dominant components in each frequency region were illustrated for coplanar impedance sensors and the measured results were compared with fitted values. As the ionic concentration increased, the value of the frequency-independent region decreased and cut-off frequencies increased. As the interelectrode spacing increased, cut-off frequencies decreased and total impedance increased. However, the width of each frequency-independent region was similar. As the electrode area increased, flow decreased but fhigh was fixed. We think that the decrease in RSol dominated over the influence of other components, which resulted in heightening flow and fhigh. The interelectrode spacing is a more significant parameter than the electrode area in the frequency characteristics of coplanar sensors. The deviation of experimentally obtained results from theoretically predicted values may result from the fringing effect of coplanar electrode structure and parasitic capacitance due to dielectric substrates. We suggest the guidelines of dominant components for sensing as design parameters.

Apparatus and method for allocating frequencies in an OFDM mobile communication system supporting high speed downlink packet access service

Abstract: An apparatus and method for allocating a frequency resource to a user equipment (UE) in an orthogonal frequency division multiplexing (OFDM) mobile communication system. A base station receives feedback information including at least mobility information from the UE, and determines from the mobility information whether the UE belongs to a fast group or a slow group. The base station allocates a frequency resource for the UE according to an open-loop solution if the UE belongs to the fast group, allocates a frequency resource for the UE according to a closed-loop solution if the UE belongs to the slow group, and transmits data for the UE using the allocated frequency resource.

Preparation and Characterization of Acrylic-Based Electronic Inks by In Situ Emulsifier-Free Emulsion Polymerization for Electrophoretic Displays

Abstract: Attempts were made to prepare monodispersed electronic ink particles by a new procedure, in situ emulsifier-free emulsion polymerization. Highly monodispersed poly(methyl methacrylate-co-ethylene glycol dimethacrylate) electronic ink particles containing blue dyes and charge control additives (E-81) were successfully prepared both in aqueous medium and in a mixture of water and methanol by emulsifier-free emulsion polymerization. On increasing either the concentration of oil blue N or E-81, the particle size decreased initially but then increased in the absence of methanol, whereas particle size progressively increases in the presence of methanol. The addition of methanol in the polymerization also influences the polymerization kinetic and the charge density of electronic ink particles. The resulting electronic inks were found to be smooth on the surfaces and particle sizes were 300−700 nm with a coefficient of variation of 0.3%. Electrophoretic mobility of the resulting electronic ink was −2.08 to −5.28 ...

The golden age: gold nanoparticles for biomedicine

Abstract: Gold nanoparticles have been used in biomedical applications since their first colloidal syntheses more than three centuries ago. However, over the past two decades, their beautiful colors and unique electronic properties have also attracted tremendous attention due to their historical applications in art and ancient medicine and current applications in enhanced optoelectronics and photovoltaics. In spite of their modest alchemical beginnings, gold nanoparticles exhibit physical properties that are truly different from both small molecules and bulk materials, as well as from other nanoscale particles. Their unique combination of properties is just beginning to be fully realized in range of medical diagnostic and therapeutic applications. This critical review will provide insights into the design, synthesis, functionalization, and applications of these artificial molecules in biomedicine and discuss their tailored interactions with biological systems to achieve improved patient health. Further, we provide a survey of the rapidly expanding body of literature on this topic and argue that gold nanotechnology-enabled biomedicine is not simply an act of ‘gilding the (nanomedicinal) lily’, but that a new ‘Golden Age’ of biomedical nanotechnology is truly upon us. Moving forward, the most challenging nanoscience ahead of us will be to find new chemical and physical methods of functionalizing gold nanoparticles with compounds that can promote efficient binding, clearance, and biocompatibility and to assess their safety to other biological systems and their long-term term effects on human health and reproduction (472 references).

Tunable metallic-like conductivity in microbial nanowire networks

Abstract: Networks of nanofilaments derived from natural amino acids can have metallic-like conductivity.

Space-Time Block Coding for Wireless Communications

Abstract: II

Theory and practice of error control codes

Abstract: algorithmics and modular computations, Theory of Codes and Cryptography (3).From an analytical 1. RE Blahut. Theory and practice of error control codes. eecs.uottawa.ca/∼yongacog/courses/coding/ (3) R.E. Blahut,Theory and Practice of Error Control Codes, Addison Wesley, 1983. QA 268. Cached. Download as a PDF 457, Theory and Practice of Error Control CodesBlahut 1984 (Show Context). Citation Context..ontinued fractions.