Author
Sanggong Yu
Bio: Sanggong Yu is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Ageratina & Genus. The author has an hindex of 6, co-authored 9 publications receiving 104 citations.
Topics: Ageratina, Genus, Agrostophyllum, Astereae, Diterpene
Papers
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TL;DR: In this paper, two terpenoids were isolated from Ageratina saltillensis including eighteen new compounds, namely, 16-hydroxy-3,4β-epoxy-5β, 10β-cis-17α,20α-cleroda-13(14)-en-15,16-olide, 3α, 4β-methoxy-4β-,16-trihydroxy, 5β,10β-Cis- 17α, 20α-, 20α-cleroda-15-oic acid
29 citations
TL;DR: In this paper, seven new and 14 known compounds were isolated from Gymnosperma glutinosum and six of them have unusual B-rings with 2-methoxyl groups.
21 citations
TL;DR: The structure of the new compound was determined by spectroscopic methods including an attached proton test experiment and CI mass spectrometry as 6,7-dimethoxy-3,5,3′,4′-tetrahydroxyflavone 3-O -apioside as discussed by the authors.
21 citations
TL;DR: Agrostophyllin, the first naturally occurring phenanthropyran derivative, was isolated from the orchid Agroophyllum khasiyanum as mentioned in this paper, and it was shown to be a phenotypic indicator of the presence of humans.
13 citations
TL;DR: In this article, six known flavonoid aglycones and the newly described 5,7,4′-trihydroxy-3,3′,5′-trimethoxyflavone were isolated from Xanthocephalum gymnospermnoides var.
8 citations
Cited by
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TL;DR: In this review the molecular, cellular, and functional bases of therapy will be emphasized taking strictly into account data appearing in the peer-reviewed literature and summarizing the main therapeutic applications of quercetin, the drug metabolism and the main drug interaction as well as the potential toxicity will be also spotlighted.
542 citations
TL;DR: This paper reviews the properties of the in vitro biological properties of conjugates that have been found in vivo on quercetin glucuronides, but also on isoflavone and catechin conjugate.
Abstract: For some flavonoids such as quercetin, isoflavones and catechins, the pathways of absorption and metabolism are now reasonably well characterised and understood. By definition, for biological activity of flavonoids to be manifest, the target tissue, which includes the blood and vascular system, must respond to the form(s) of flavonoid that it encounters. Bioavailability studies have shown that the circulating form of most flavonoids is as conjugates, with a few notable exceptions. There have been several recent papers on the in vitro biological properties of conjugates that have been found in vivo. This paper reviews the properties of these conjugates. Most of the information currently available is on quercetin glucuronides, but also on isoflavone and catechin conjugates. In addition to the biological properties of the conjugates, the partition coefficients and methods of synthesis are also presented.
209 citations
Book•
27 Apr 2001
TL;DR: The Flavonoids as Indicators of the Evolutionary Process and Hybridization and Introgression and Flavonoid Relationships with other Families.
Abstract: Section I. Introduction to the Sunflower Family.- 1. Biology and Distribution.- 2. Classification, Phylogeny and Biogeography.- Section II. Introduction to the Flavonoids.- 3. The Use of Flavonoids as Taxonomic Markers.- 4. Structural Variation of the Flavonoids of Asteraceae.- 5. Biosynthesis of Flavonoids.- 6. Biological Functions of Flavonoids.- Section III. Flavonoid Data.- 7. Flavonoids of Anthemideae.- 8. Flavonoids of Astereae.- 9. Flavonoids of Calenduleae and Cardueae.- 10. Flavonoids of Eupatorieae.- 11. Flavonoids of Heliantheae s.l.- 12. Flavonoids of Inuleae s.l.- 13. Flavonoids of Lactuceae.- 14. Flavonoids of Mutisieae and Barnadesioideae.- 15. Flavonoids of Senecioneae.- 16. Flavonoids of Tageteae.- 17. Flavonoids of Vernonieae and Liabeae.- Section IV. Efficacy of Flavonoids at Different Taxonomic Levels.- 18. Flavonoids at the Subfamilial Level.- 19. Flavonoids at the Tribal Level.- 20. Flavonoids at the Subtribal Level.- 21. Flavonoids at the Generic Level.- 22. Flavonoids at the Specific Level.- 23. Flavonoids at Infraspecific Levels.- Section V. Flavonoids as Indicators of the Evolutionary Process.- 24. Flavonoids and Populational Variation.- 25. Flavonoids and Hybridization and Introgression.- Section VI. Flavonoids and Phylogeny.- 26. Flavonoid Relationships with other Families.- 27. Evolution of the Flavonoid System in Asteraceae.- Addendum.- References.- Common Names of Flavonoids Used in This Book and Their Equivalents.- Chemical Index.- Taxon Index.
164 citations
TL;DR: Nanoformulations of quercetin have shown promising results in its uptake by the epithelial system as well as enhanced delivery to the target site, and various desirable measures for its use as a promising onco-therapeutic agent are highlighted.
Abstract: Phytochemicals as dietary constituents are being explored for their cancer preventive properties. Quercetin is a major constituent of various dietary products and recently its anti-cancer potential has been extensively explored, revealing its anti-proliferative effect on different cancer cell lines, both in vitro and in vivo. Quercetin is known to have modulatory effects on cell apoptosis, migration and growth via various signaling pathways. Though, quercetin possesses great medicinal value, its applications as a therapeutic drug are limited. Problems like low oral bioavailability and poor aqueous solubility make quercetin an unreliable candidate for therapeutic purposes. Additionally, the rapid gastrointestinal digestion of quercetin is also a major barrier for its clinical translation. Hence, to overcome these disadvantages quercetin-based nanoformulations are being considered in recent times. Nanoformulations of quercetin have shown promising results in its uptake by the epithelial system as well as enhanced delivery to the target site. Herein we have tried to summarize various methods utilized for nanofabrication of quercetin formulations and for stable and sustained delivery of quercetin. We have also highlighted the various desirable measures for its use as a promising onco-therapeutic agent.
133 citations
TL;DR: In this paper, the 13 C NMR spectra of polyhydroxyflavones were systematically examined by using about 70 examples which have a 4methoxyphenyl B-ring.
120 citations